Sökning: "suprachiasmatic"
Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet suprachiasmatic.
1. Effects of aging and inflammatory molecules on the suprachiasmatic circadian clock
Sammanfattning : The suprachiasmatic nucleus (SCN) is considered the master circadian pacemaker in the mammalian brain and is vital for generating physiological and behavioral circadian rhythms. During aging and inflammatory conditions the circadian system is frequently affected, but relatively little is known about the mechanisms underlying such effects. LÄS MER
2. Circadian rhythm dysfunction in the suprachiasmatic nucleus : effects of Trypanosoma brucei brucei infection and inflammatory cytokines
Sammanfattning : Alterations in the mammalian circadian pacemaker, the hypothalamic suprachiasmatic nuclei (SCN), were studied in an experimental rat model of African trypanosomiasis, or sleeping sickness, caused by infections with subspecies of Trypanosoma brucei (T b). Characteristic signs of the disease are marked disturbances in circadian rhythms, such as a fragmentation of the sleep-wake cycle. LÄS MER
3. In the right place and at the right time : cellular and functional neuroanatomy of endocannabinoids and neuropeptides
Sammanfattning : A plethora of chemical signals, including endocannabinoids and neuropeptides, enable neuronal communication beyond the classical neurotransmitters. Many of these molecules are also expressed during (early) brain development, helping neurons to mature and neuronal circuits to take form. LÄS MER
4. Effects of excess glucocorticoids on neural cell fate : long lasting consequences of adverse prenatal factors
Sammanfattning : The developing nervous system is particularly vulnerable to high level of glucocorticoids (GCs). Excess GCs is often associated with decreased birth weight in relation to gestational age, and to increased risk of psychiatric disorders, like depression, later in life. LÄS MER
5. Anatomical studies of the dopamine system in the hypothalamus and the pituitary gland
Sammanfattning : The hypothalamus is a small, evolutionarily conserved brain region, necessary for our survival as individuals and as a species. It collects various sensory inputs, process them to maintain homeostasis and to overcome stressors, and generates outputs that affect the autonomic nervous system, the endocrine system and somatomotor behaviors. LÄS MER