Sökning: "superoxide dismutase"

Visar resultat 16 - 20 av 73 avhandlingar innehållade orden superoxide dismutase.

  1. 16. Experimental studies on thrombosis and thrombolysis : With special reference to importance of lys-plasminogen, active site thrombin inhibitors and stable fish oil

    Författare :Liying Chen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Thrombolysis; thrombosis; recombinant tissue-type plasminogen activator; lys- and glu-plasminogen; aspirin; thrombin inhibitors; platelets; superoxide dismutase; stable fish oil; Kirurgi; Surgery; Kirurgi; rättsmedicin; Forensic Medicine;

    Sammanfattning : Dissolution and prevention of thrombus in the atherosclerotic coronary artery have become an important part of treatment therapy of acute myocardial infarction. However, the currently most effective thrombolytic agent, recombinant tissue-type plasminogen activator (rt-PA), only elicits 80% recanalization of thrombotically occluded coronary arteries and early occlusion occurs in about 40% of successfullyrecanalized vessels. LÄS MER

  2. 17. Effects of Antioxidant and Lipid Lowering Treatment on Risk Factors for Cardiovascular Disease : With special reference to Mixed Tocopherols and Stable Fish Oil

    Författare :Meilin Liu; Afaf Kamal-Eldin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Cardiovascular disease; Antioxidants; Tocopherols; Endothelial constitutive nitric oxide synthase; Superoxide dismutase; Protein kinase C; Fish oils; Fatty acids; Simvastatin; Lipoprotein; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; rättsmedicin; Forensic Medicine;

    Sammanfattning : Vitamin E in food, polyunsaturated fatty acids (PUFAs) and lipid lowering treatment with statins have been found to decrease the risk for cardiovascular disease (CVD) and cardiac death. However, clinical trials revealed no beneficial effect of intake of alpha-tocopherol alone. LÄS MER

  3. 18. Fetal Outcome in Experimental Diabetic Pregnancy

    Författare :Sheller Zabihi; Ulf Eriksson; Michael Welsh; Elisabeth (Lisa) Persson; Uppsala universitet; []
    Nyckelord :Cell biology; Rat; Mouse; TG; KO; Diabetes in Pregnancy; Embryo; Folic acid; Superoxide dismutase; Catalase; Glutathione peroxidase; Vascular endothelial growth factor-A; Folate binding protein-1; Bax; Bcl-2; Caspase-3; P53; Pax-3; Blood flow; Cellbiologi;

    Sammanfattning : Women with pregestational diabetes have a 2-5 fold increased risk of giving birth to malformed babies compared with non-diabetic women. Diabetes-induced oxidative stress in maternal and embryonic tissues has been implicated in the teratogenic process. LÄS MER

  4. 19. Misfolded superoxide dismutase-1 in sporadic and familial Amyotrophic Lateral Sclerosis

    Författare :Karin Forsberg; Thomas Brännström; Irina Alafuzoff; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALS; SOD-1 motor neuron; protein misfolding; intranuclear; antibodies; CNS; brain; patologi; Pathology;

    Sammanfattning : Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative syndrome of unknown etiology that most commonly affects people in middle and high age. The hallmark of ALS is a progressive and simultaneous loss of upper and lower motor neurons in the central nervous system that leads to a progressive muscle atrophy, paralysis and death usually by respiratory failure. LÄS MER

  5. 20. Active oxygen involvement in developmental processes in Populus : with emphasis on HipI-superoxide dismutase

    Författare :Vaibhav Srivastava; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : In plants, oxidative stress is result of disruption of the cellular redox metabolism and is caused by a variety of stress conditions (abiotic and/or biotic). This leads to the induction of several mechanisms that protect against disruption of the redox balance, as well as mechanisms to assist in recovery from toxicity/damage caused by increased cellular levels of reactive oxygen species (ROS). LÄS MER