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Visar resultat 1 - 5 av 73 avhandlingar som matchar ovanstående sökkriterier.
1. Superoxide dismutase : radiobiological significance : occurrence in human tissues, tumours and tumour cell-lines
Sammanfattning : .... LÄS MER
2. Superoxide dismutase 1 and cataract
Sammanfattning : Light and oxygen generate harmful reactive oxygen species (ROS) in the lens, causing biochemical changes that gradually disarrange the lens fibres resulting in light scattering and loss of transparency. In the healthy eye, this chronic exposure to oxidative stress may lead to age-related cataract. LÄS MER
3. Protein folding studies of human superoxide dismutase and ALS associated mutants
Sammanfattning : Proteins are among the most abundant biological macromolecules. The cellular machinery is coupled to exact structural shape and properties of the more than 100 000 different proteins. Still, proteins can sometimes completely change their character and as a result trigger neuro degenerative disease. LÄS MER
4. From Time-Averaged to Time-Resolved Crystallography: Studies on Superoxide Dismutase and Myoglobin
Sammanfattning : We have studied protein motions with nanosecond time-resolved crystallography. The release of carbon monoxide from its complex with myoglobin (MbCO) was triggered by nanosecond laser pulses. X-ray data were collected with time delays ranging from 4 ns to 1.9 ms using the Laue method, at the European Synchrotron Radiation Facility in Grenoble. LÄS MER
5. Protein Engineering of Extracellular Superoxide Dismutase : Characterization of Binding to Heparin and Cellular Surfaces
Sammanfattning : Accumulating evidence indicates that oxygen free radicals are involved in many diseases and pathological conditions, such as aging, inflammation, reperfusion damage of ischemic tissue and various cardiovascular diseases. Extracellular superoxide dismutase (ECSOD) thus plays a major role in the maintenance of cells by providing protection against these toxic substances in the extracellular space. LÄS MER