Sökning: "superantigen"
Visar resultat 11 - 15 av 34 avhandlingar innehållade ordet superantigen.
11. Severe Streptococcus pyogenes disease in Europe; epidemiology and clinical manifestations
Sammanfattning : Streptococcus pyogenes, gives rise from mild skin infections and pharyngitis, to life threatening infections like bacteraemia, cellulitis, puerperal sepsis, meningitis, pneumonia, necrotizing fasciitis (NF), and streptococcal toxic-like shock syndrome (STSS), or nonsuppurative sequelae, rheumatic fever and glomerulonephritis. In 2002, the first multinational network for invasive GAS disease surveillance was initiated by the EU-funded Strep-EURO project. LÄS MER
12. On the induction and function of Foxp3+ regulatory T cells
Sammanfattning : This thesis is based on three original papers with the overall aim to study the mechanisms of induction and function of Foxp3+CD4+CD25+ regulatory T cells. Regulatory T cells induce down-modulation of costimulatory molecules CD80 and CD86 on dendritic cells in vitro. LÄS MER
13. The ups and downs of T cells The role of costimulatory molecules in the modulation of T cell responses
Sammanfattning : T cell activation requires the combination of antigen in the context of MHC and costimulatory molecules to induce a functional immune response. For our studies, we primarily utilized superantigens (SAg) that bind MHC class II molecules as first signal. LÄS MER
14. Regulation of superantigen-induced cytokine production
Sammanfattning : .... LÄS MER
15. Immunological mechanisms in response to antibody-targeted superantigen tumor therapy
Sammanfattning : .... LÄS MER