Sökning: "sulfotransferase"

Visar resultat 11 - 15 av 20 avhandlingar innehållade ordet sulfotransferase.

  1. 11. Cellular regulation of heparan sulfate structure and function

    Författare :Fariba Safaiyan; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Heparan sulfate; structure; biosynthesis; sulfation; Biokemi; Biochemistry; Biokemi; Medical and Physiological Chemistry; medicinsk och fysiologisk kemi;

    Sammanfattning : Heparan sulfate (HS) is a sulfated glycosaminoglycan found on cell surfaces and in the extracellular matrix as HS proteoglycans. HS is synthesized as a polymer of alternating glucuronic acid and N-acetylglucosamine units. LÄS MER

  3. 12. Functions of Heparan Sulfate During Mouse Development : Studies of Mice with Genetically Altered Heparan Sulfate Biosynthesis

    Författare :Maria Ringvall; Lena Kjellén; Erik Forsberg; Ulf Lindahl; Erika Gustafsson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; embryonic development; gene targeting; lung development; ossification; heparan sulfate; heparin; N-deacetylase N-sulfaotransferase; NDST; proteoglycan; morphogen; biosynthesis; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi;

    Sammanfattning : Heparan sulfate (HS) is a ubiquitous polysaccharide on the cell surface and in the extracellular matrix. HS is an important actor in the regulation of cell signaling, especially in the developing embryo. LÄS MER

  4. 13. Understanding Heparan Sulfate Biosynthesis and Functional Implications of Heparanase

    Författare :Tianyi Song; Dorothe Spillmann; Cathrine Merry; Uppsala universitet; []
    Nyckelord :Heparan sulfate; biosynthesis; heparanase; lipid metabolism; cancer; cell adhesion; apoptosis.; Molekylär medicin;

    Sammanfattning : Heparan sulfate (HS) proteoglycans are present on the plasma membrane of all animal cells studied so far and are a major component of extracellular matrices. Heparanase is an endo-ß-glucuronidase that cleaves HS chains at internally located ß-glucuronidic linkages1. LÄS MER

  5. 14. FROM GENE TO STRUCTURE: Formation of Iduronic Acid in Dermatan Sulfate by Two DS-epimerases

    Författare :Benny Pacheco; Matrixbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : During embryonic development and adult life a wide range of cell behaviors such as differentiation, proliferation and migration are in effect to maintain tissue integrity and function. An integral part of these dynamic processes is the interplay between the cells and their environment, i.e. the extracellular space. LÄS MER

  7. 15. Dopachrome and aminochrome, the oxidized metabolites of dopa and dopamine : studies on the molecular mechanisms underlying their reduction and conjugation with glutathione

    Författare :Sofia Baez; Francisco Solano Munoz; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Sammanfattning : Dopamine, like other catecholamines can be oxidized to the corresponding ortho-quinone, which undergoes cyclization of its amino chain to cyclized dopamine ortho-quinone (aminochrome). Both o-quinones are toxic metabolites that may contribute to neurotoxic effects of these catecholamines. LÄS MER