Sökning: "sulfotransferase"

Visar resultat 1 - 5 av 19 avhandlingar innehållade ordet sulfotransferase.

  1. 1. In Vitro Studies of the Substrate Specificities of Heparan Sulfate 2-O- and 6-O-sulfotransferases

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Emanuel Smeds; Uppsala universitet.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; heparan sulfate; heparin; sulfotransferase; 2-O-sulfotransferase; 6-O-sulfotransferase; polysaccharide biosynthesis; glycosaminoglycan; O-sulfotransferase; proteoglycan; Biokemi; MEDICINE Chemistry Biochemistry; MEDICIN Kemi Biokemi;

    Sammanfattning : Heparan sulfate (HS), a linear negatively charged polysaccharide located at the cell surface and in the extracellular matrix, interacts with, and thereby regulates the functions of numerous proteins. HS-protein interactions depend on the fine structure of HS, especially its sulfation pattern. LÄS MER

  2. 2. Formation of Iduronic Acid during Chondroitin/Dermatan Sulfate Biosynthesis

    Detta är en avhandling från Lund University: Faculty of Medicine

    Författare :Emil Tykesson; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GLYCOSAMINOGLYCAN; CHONDROITIN; DERMATAN; EPIMERASE; SULFOTRANSFERASE; GLYCOSAMINOGLYCAN; CHONDROITIN SULFATE; DERMATAN SULFATE; EPIMERASE; SULFOTRANSFERASE;

    Sammanfattning : All animals and some bacteria can synthesize linear polysaccharides with a backbone of repeating disaccharideunits, called glycosaminoglycans (GAGs). The GAGs are either attached to a protein core, as in proteoglycans (PGs), or exist as free polymer chains, as in hyaluronan. LÄS MER

  3. 3. Biosynthesis of Dermatan Sulphate. Enzymatic mechanism and role of cytokines

    Detta är en avhandling från Kerstin Tiedemann, Dept of Cell and Molecular Biology, Box 94, 221 00 Lund, Sweden

    Författare :Kerstin Tiedemann; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dermatan sulphate; 4-O-sulfotransferase; Co-polymeric structure; biglycan; decorin; Biochemistry; Biokemi; C5-epimerase; Metabolism;

    Sammanfattning : Dermatan sulphate is a prominent feature of several different proteoglycans and occurs in almost every tissue of the body. It is an unbranched polymer containing the repeating disaccharide unit of N-acetylgalactosamine and D-glucuronic acid or L-iduronic acid. LÄS MER

  4. 4. Heparan Sulfate Biosynthesis – Clues from Knockout Mice

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Johan Ledin; Lena Kjellén; John Gallagher; [2004]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; heparan sulfate; biosynthesis; gene targeting; embryonic development; proteoglycans; NDST; N-deacetylase N-sulfotransferase; Cell- och molekylärbiologi; NATURAL SCIENCES Biology Cell and molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi;

    Sammanfattning : In the extracellular space, many specialized proteins are located to support cells and to mediate cell-cell signalling. One class of such molecules is heparan sulfate (HS) proteoglycans, which are proteins with different properties and locations but all of them decorated with long unbranched HS polysaccharide chains. LÄS MER

  5. 5. Glycosaminoglycan Biosynthesis in Zebrafish

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Beata Filipek-Górniok; Lena Kjellén; Johan Ledin; Kay Grobe; [2015]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heparan sulfate; chondroitin dermatan sulfate; biosynthesis; development; N-deacetylase N-sulfotransferase; glycosyltransferases; morpholino; CRISPR-Cas9;

    Sammanfattning : Proteoglycans (PGs) are composed of highly sulfated glycosaminoglycans chains (GAGs) attached to specific core proteins. They are present in extracellular matrices, on the cell surface and in storage granules of hematopoietic cells. LÄS MER