Sökning: "sulfadoxine pyrimethamine"
Visar resultat 1 - 5 av 13 avhandlingar innehållade orden sulfadoxine pyrimethamine.
1. Development of Analytical Methods for the Determination of Antimalarials in Biological Fluids
Sammanfattning : The aim of this thesis was to develop analytical methods for measuring antimalarial drugs in biological fluids. Solid phase extraction (SPE) was used for the enrichment and purification of the drugs. LÄS MER
2. Fixed-dose chloroquine and sulfadoxine/pyrimethamine treatment of malaria : outcome and pharmacokinetic aspects
Sammanfattning : Background: A pre-packaged fixed-dose formulation of chloroquine (CQ) and sulfadoxine/pyrimethamine (SIP) combination (Homapak) is widely used for the treatment of falciparum malaria in the Home Based Management of Fevers program for Ugandan children. Until the present study, the efficacy, pharmacokinetics and drug interactions of the dose regimen of the product were not known. LÄS MER
3. Optimization of intermittent preventive therapy for malaria during pregnancy : effectiveness of dihydroartemisinin-piperaquine versus sulfadoxine-pyrimethamine
Sammanfattning : Malaria is a Tropical disease caused by different parasites species of genius Plasmodium. Because of pregnancy associated lowered immunity, women who are pregnant are at higher risk to malaria infection than non-pregnant women. LÄS MER
4. Managing childhood malaria in rural Tanzania : focusing on drug use and resistance
Sammanfattning : Background: Malaria is a leading cause of death in underfive children in Africa. Due to the spread of chloroquine (CQ) resistance, sub-Saharan African countries such as Tanzania have changed their malaria treatment policies. In 2001 Tanzania replaced CQ with sulfadoxine/pyrimethamine (SP) as first line malaria treatment. LÄS MER
5. Exploring malaria case mangement of underfive children at households and public primary health care facilities in Kibaha district, Tanzania
Sammanfattning : Background: Chloroquine (CQ) was the first line drug for treating malaria in Tanzania until 2001 when it was replaced with sulfadoxine/pyrimethamine (SP). The first four studies (I -IV) were conducted before the policy change, and the last one (V) after. LÄS MER