Sökning: "sub-inhibitory"

Hittade 5 avhandlingar innehållade ordet sub-inhibitory.

  1. 1. Antibiotic sensitivity and horizontal gene transfer in Escherichia coli - A genome-wide perspective

    Författare :Martin Palm; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; antibiotics; antibiotic resistance; Escherichia coli; heavy metals; bacterial conjugation; pangenome; sub-inhibitory;

    Sammanfattning : Since their discovery in the early 20th century, antibiotics have truly revolutionized human medicine. They have allowed us to treat diseases that were previously untreatable and have become a staple of modern medicine. However, along with the human use of antibiotics pathogens resistant to antibiotics emerged. LÄS MER

  3. 2. On the pathogenesis of infections associated with percutaneous osseointegrated orthopaedic implants

    Författare :Magdalena Zaborowska; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; osseointegration; amputation prosthesis; implant-associated infection; biofilm; staphylococci; extracellular vesicles; host defence; cytokines; cell death;

    Sammanfattning : Orthopaedic implants enable the restitution of locomotor function and improve the quality of life of many people. However, biomaterial-associated infection may occur due to the propensity of microorganisms to adhere and colonize implant surfaces. LÄS MER

  4. 3. Trehalose metabolism and stress resistance in Aspergillus niger

    Författare :Åsa Svanström; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Food spoilage by filamentous fungi, moulds, is a global issue of great significance. Mould growth can cause food losses due to deterioration, and adverse health effects due to toxin production. Conidia, asexual spores, are the main factors of dispersal and infection in most food-relevant moulds. LÄS MER

  5. 4. It Takes Two to Tango : Bacterial heterogeneity and host cell features govern Salmonella infection

    Författare :Viktor Ek; Mikael E. Sellin; Francisco García del Portillo; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Salmonella; swimming; swim pattern; targetting; virulence; invasion; host-pathogen interactions; epithelium; epithelial cells; macrophages; monocytes; monolayer; flagella; genome; genetic; barcoding; discreet-invasion; shape; morphology; antibiotics; persistence; Mikrobiologi; Microbiology;

    Sammanfattning : Salmonella enterica serovar Typhimurium (S.Tm) causes enterocolitis with significant worldwide morbidity and mortality. The general aim of this thesis is to investigate variation in host cell invasion mechanisms used by S.Tm across different host cell contexts, as well as the influence of bacterial cell-cell heterogeneity on invasion-relevant S. LÄS MER

  7. 5. Neutrophil interactions with Streptococcus pyogenes and Staphylococcus aureus

    Författare :Julia Uhlmann; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Streptococcus pyogenes and Staphylococcus aureus are Gram-positive bacteria that share many features, including clinical presentations and pathogenic mechanisms, and yet, they still have unique properties. They both cause diseases ranging from uncomplicated infections to severe invasive diseases, such as sepsis and toxic shock syndrome, as well as severe tissue infections including necrotizing fasciitis and necrotizing pneumonia. LÄS MER