Sökning: "structural modeling"
Visar resultat 1 - 5 av 386 avhandlingar innehållade orden structural modeling.
1. Structural modeling of membrane transporter proteins
Sammanfattning : A fundamental process of all living organisms - the transport of molecules across cellular membranes through membrane transport proteins - is investigated.After a brief review of general properties of biological membranes follows a recollection of the major methods of membrane transport that Nature utilizes (Chapter 1). LÄS MER
2. Crustal architecture of the Kiruna mining district : Structural framework, geological modeling, and physical rock property distribution
Sammanfattning : Rapid technological advancements and growing environmental consciousness created a shifting dynamic of metal demand within the context of contemporary global challenges. The metals play a pivotal role in this transformation and remarkable surge in demand is expected. LÄS MER
3. New Paradigms in GPCR Drug Discovery : Structure Prediction and Design of Ligands with Tailored Properties
Sammanfattning : G protein-coupled receptors (GPCRs) constitute a large superfamily of membrane proteins with key roles in cellular signaling. Upon activation by a ligand, GPCRs transduce signals from the extracellular to the intracellular environment. LÄS MER
4. Imaging and modeling the cardiovascular system
Sammanfattning : Understanding cardiac pumping function is crucial to guiding diagnosis, predicting outcomes of interventions, and designing medical devices that interact with the cardiovascular system. Computer simulations of hemodynamics can show how the complex cardiovascular system is influenced by changes in single or multiple parameters and can be used to test clinical hypotheses. LÄS MER
5. Major Intrinsic Proteins - Structure, function, interactions
Sammanfattning : Major intrinsic proteins, also referred to as aquaporins (AQPs) are localized in membranes of all domains of life to increase the permeability to water or other small, polar molecules. Several monophyletic groups can be discerned in this large and divergent protein superfamily. LÄS MER