Sökning: "structural model"

Visar resultat 1 - 5 av 1816 avhandlingar innehållade orden structural model.

  1. 1. Quantifying Structural Change : A Model Based Approach

    Författare :Birgitta Törnkvist; Umeå universitet; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  2. 2. Improved pharmacometric model building techniques

    Författare :Radojka Savic; Mats Karlsson; Siv Jönsson; Matt Hutmacher; Uppsala universitet; []
    Nyckelord :Model building; Absorption model; Transit compartment model; Nonparametric method; Extended grid method; Semiparametric; Distribution transformation; Shrinkage; Model diagnostics;

    Sammanfattning : Pharmacometric modelling is an increasingly used method for analysing the outcome from clinical trials in drug development. The model building process is complex and involves testing, evaluating and diagnosing a range of plausible models aiming to make an adequate inference from the observed data and predictions for future studies and therapy. LÄS MER

  3. 3. Strukturomvandling och social utslagning : en analys av sambanden mellan social struktur och social missanpassning och utslagning under perioden 1860-1975

    Författare :Willy Frick; Umeå universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; structural change; social elimination; social maladjustment; crime; alcoholism; budding model; expansion model; social integration; social control; personality development;

    Sammanfattning : Structural changes in society have often been related to social problems such as crime, alcoholism and social elimination. In this analysis of the development of social elimination in Sweden during the period 1860-1975, which is mainly based on official data, it is demonstrated that there is not always a causal relationship between structural change and such social problems. LÄS MER

  4. 4. Transthyretin and the transthyretin-related protein: A structural study

    Författare :Erik Lundberg; A. Elisabeth Sauer-Eriksson; Lennart Sjölin; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Transthyretin; Transthyretin-related protein; X-ray crystallography; Protein structure; Amyloidosis; Structural biology; Strukturbiologi;

    Sammanfattning : Transthyretin (TTR) is one of several proteins involved in amyloid disease in humans. Unknown conformational changes of the native state of TTR result in aggregation of TTR molecules into amyloid fibrils, which accumulate in extracellular tissues. This may result in different clinical symptoms, e.g. LÄS MER

  5. 5. Stochastic model updating and model selection with application to structural dynamics

    Författare :Majid Khorsand Vakilzadeh; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Finite element model; Bayesian model selection; Bayesian model updating; stochastic simulation; Bootstrapping; Subspace system identification; Uncertainty quantification;

    Sammanfattning : Uncertainty induced by our incomplete state of knowledge about engineering systems and their surrounding environment give rise to challenging problems in the process of building predictive models for the system behavior. One such challenge is the model selection problem, which arises due to the existence of invariably multiple candidate models with different mathematical forms to represent the system behavior, and so there is a need to assess their plausibility based on experimental data. LÄS MER