Sökning: "structural analysis of polysaccharides"

Visar resultat 1 - 5 av 31 avhandlingar innehållade orden structural analysis of polysaccharides.

  1. 1. Structural and Conformational Studies of Oligo- and Polysaccharides

    Författare :Mona Zaccheus; Göran Widmalm; Christina De Castro; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NMR spectroscopy; structural analysis; conformational analysis; carbohydrates; polysaccharides; organisk kemi; Organic Chemistry;

    Sammanfattning : The focus of this thesis is to examine the structural properties of polysaccharides produced by bacteria, as well as the dynamic and conformational behavior of a synthetically derived oligosaccharide.The primary structures of the O-polysaccharide repeating units of four different Escherichia coli (E. LÄS MER

  3. 2. Tales from the Sweet Side of Life : Structure and dynamics of carbohydrate-based systems

    Författare :Alessandro Ruda; Göran Widmalm; Jesús Jiménez Barbero; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; carbohydrates; nuclear magnetic resonance; molecular dynamics; glycans; conformational analysis; structure elucidation; protein-glycan interactions; Organic Chemistry; organisk kemi;

    Sammanfattning : The field of glycomics has experienced significant developments in the last few decades, revealing a profound and elaborate language behind the intrinsic complexity of the glycans structures. This ‘sugar code’ is at the basis of intercellular interaction and recognition. For this language to be understood, its chemical basis must be unveiled. LÄS MER

  4. 3. Structural and Interaction Studies of Bacterial Polysaccharides by NMR Spectroscopy

    Författare :Eva-Lisa Nordmark; Göran Widmalm; Sven Müller-Loennies; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bacterial polysaccharides; NMR; interaction studies; structural studies; Escherichia coli; Salmonella enteritidis; Streptococcus thermophilus; Propionibacterium freudenreichii; Pseudoalteromonas aliena; P22 TSP; Organic chemistry; Organisk kemi;

    Sammanfattning : An introduction to bacterial polysaccharides and the methods for structural determination are described in the first two parts of the thesis.In a structural elucidation of bacterial polysaccharides NMR experiments are important as is component analysis. A short description of immunochemical methods such as enzyme immunoassays is included. LÄS MER

  5. 4. Identification and characterisation of chitin and cellulose synthases in oomycetes : New tools for biochemical studies and structure determination

    Författare :Stefan Klinter; Vincent Bulone; Lauren S. McKee; Mirjam Czjzek; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; biochemical characterisation; cellulose synthase; chitin synthase; in vitro activity assay; microtubule-interacting and trafficking domain; nanoparticle; oomycetes; phylogenetic analysis; yeast engineering; biokemisk karakterisering; cellulosasyntas; kitinsyntas; in vitro aktivitetsanalys; mikrotubulus-interagerande och -trafikerande domän; nanopartikel; oomyceter; fylogenetisk analys; jäst proteinteknik; Bioteknologi; Biotechnology;

    Sammanfattning : Despite resembling ‘true’ fungi in terms of morphological features, oo­mycetes form a distinct eukaryotic lineage of filamentous microorganisms that belongs to the stramenopiles, a group of protists also comprising the closely-related brown algae and diatoms. Many oomycetes are devastating pathogens of plants and animals, globally causing significant economic los­ses in the agriculture and aquaculture industries, and posing considerable environmental damage to natural ecosystems. LÄS MER

  7. 5. Assembling and Unraveling Carbohydrates Structures : Conformational analysis of synthesized branched oligosaccharides

    Författare :Thibault Angles d'Ortoli; Göran Widmalm; Christian Marcus Pedersen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Convergent carbohydrate synthesis; Super-armed donors; Glycosylation; Conformational analysis; NMR; Chemical shift prediction; organisk kemi; Organic Chemistry;

    Sammanfattning : Advances in the elaboration of vaccines and enzyme inhibitors rely on acquiring more knowledge about protein-carbohydrate binding events. Furthermore, the relationships between biological function and the three-dimensional properties of large glycans can be studied by focusing on the structural components they contained, namely, by scaling down the system under analysis. LÄS MER