Sökning: "stroma"

Visar resultat 11 - 15 av 194 avhandlingar innehållade ordet stroma.

  1. 11. Distal cholangiocarcinoma - from novel biomarkers to clinical management and outcome

    Författare :Johannes Byrling; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Distal cholangiocarcinoma; biliary tract cancer; periampullary cancer; pancreatoduodenectomy; lymph node metastasis; stroma; SPARC; THBS2; biomarker; mass spectrometry; Diagnosis; histopathology;

    Sammanfattning : Cholangiocarcinoma is an aggressive malignacy arising from the biliary tree. Anatomical subtypes ofcholangiocarcinoma differs in tumor biology and clinical management. Distal cholangiocarcinoma (dCCA)originates from the common bile duct. LÄS MER

  3. 12. Targeting the prostate tumor microenvironment and vasculature : the role of castration, tumor-associated macrophages and pigment epithelium-derived factor

    Författare :Sofia Halin; Anders Bergh; Pernilla Wikström; Stina Rudolfsson; Carl-Henrik Heldin; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; angiogenesis; castration therapy; microenvironment; stroma; tumor-associated macrophages; pigment epithelium-derived factor; PEDF; vasculature; Pathology; Patologi; patologi; Pathology;

    Sammanfattning : BACKGROUND: Prostate cancer is the most common cancer among Swedish men. For patients with metastatic prostate cancer the standard therapy is castration, a treatment that initially provides symptomatic relief but unfortunately is not curative. New therapeutic targets for advanced prostate cancer are therefore needed. LÄS MER

  4. 13. Tissue remodelling proteases as prognostic factors in colon and rectal cancer

    Författare :Marcus Langenskiöld; Göteborgs universitet; []
    Nyckelord :extracelluar matrix; survival; staging; colorectal cancer; mucosa; stroma;

    Sammanfattning : Background: Colorectal cancer is the third most common cancer in Sweden and the main treatment is surgery. The TNM classification is the principal staging tool, although insufficient in identifying all patients with poor survival. LÄS MER

  5. 14. Prostate Cancer Tissue Biomarkers

    Författare :Felicia-Elena Marginean; Malmö Urologisk cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; : Prostate cancer; biomarkers; STAT3; stroma; metastases; Artificial Intelligence; Gleason score; Biochemical recurrence;

    Sammanfattning : .... LÄS MER

  7. 15. Basement membrane collagens in pancreatic cancer : novel stroma-derived tumor markers and regulators of cancer cell growth

    Författare :Daniel Öhlund; Malin Sund; Peter Naredi; Matthias Löhr; Umeå universitet; []
    Nyckelord :Pancreatic cancer; tumor marker; basement membrane; type IV collagen; type XVIII collagen; matrix metalloproteinase; integrin; autocrine loop; tumor stroma; kirurgi; Surgery;

    Sammanfattning : Background: Among the common malignancies, pancreatic cancer has the shortest long-term survival. The aggressive, rapid, and infiltrative growth pattern of pancreatic cancer, together with the lack of specific symptoms, often leads to late diagnosis. LÄS MER