Sökning: "striatum"

Visar resultat 21 - 25 av 256 avhandlingar innehållade ordet striatum.

  1. 21. Dopamine and the regulation of movements - significance of nigral and striatal dopamine release in normal, hemiparkinsonian and dyskinetic rats

    Författare :Daniel Andersson; Göteborgs universitet; []
    Nyckelord :dopamine; substantia nigra; striatum; L-DOPA; dyskinesias; serotonin;

    Sammanfattning : Introduction: The nigrostriatal dopamine (DA) containing neurones are a pivotal component in the basal ganglia, a network that regulates movement. Degeneration of these neurones causes the cardinal symptoms of Parkinson’s disease (PD). LÄS MER

  3. 22. Proteomic Characterization of Induced Developmental Neurotoxicity

    Författare :Henrik Alm; Lennart Dencker; R Stuart Cobb; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteomics; Brain Development; Neurotoxicity; 2D-DIGE; Brain Growth Spurt; Polybrominated Diphenyl Ether; Neonatal; Striatum; Hippocampus; Cerebral Cortex; Parkinsonism; Dyskinesia; Toxicology; Toxikologi; Toxicology; Toxikologi;

    Sammanfattning : The developing brain goes through a number of developmental periods during which it displays an increased sensitivity to exogenous disturbances. On such period is the so called “Brain growth spurt” (BGS) which in humans takes place starting from the third trimester of pregnancy and throughout the first few years of life. LÄS MER

  4. 23. Development of the Mouse Lateral Telencephalon

    Författare :Jan Stenman; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; teratologi; embryologi människa ; Utvecklingsbiologi; ontogeny; embryology human ; teratology; Development biology; progenitor domains; striatum; olfactory bulb; amygdala; development; telencephalon; patterning; mouse;

    Sammanfattning : The telencephalon is the most rostral part of the vertebrate central nervous system and is comprised of a number of structures important for voluntary movements and higher cognitive processes. This thesis focuses on the genetic mechanisms that control development of a number of telencephalic structures: the olfactory bulb, the striatum as well as the lateral and basolateral nuclei of the amygdala. LÄS MER

  5. 24. Toward a restorative therapy for Parkinson´s disease. Studies on the functional efficacy of intracerebral fetal cell transplants and GDNF delivery

    Författare :Christian Winkler; Neurobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; neuropsychology; Neurologi; neuropsykologi; neurofysiologi; neurophysiology; dyskinesia; L-DOPA; behaviour; transplantation; neuroprotection; GDNF; substantia nigra; striatum;

    Sammanfattning : Parkinson´s disease is characterized by a progressive degeneration of the nigral dopaminergic system. Treatment of disease symptoms using L-DOPA frequently induces side effects such as L-DOPA-induced dyskinesia. LÄS MER

  7. 25. On the mechanisms and physiological function of somatodendritic dopamine release in substantia nigra

    Författare :Filip Bergquist; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Calcium channels; dopamine release; microdialysis; rotarod; SNARE; striatum; substantia nigra;

    Sammanfattning : Somatodendritic release of neurotransmitters is a neuronal function that is poorly understood in comparison with the more abundant terminal release. This study aimed at characterising somatodendritic dopamine release in substantia nigra in terms of release mechanisms and possible physiological function in motor control. LÄS MER