Sökning: "striatal plasticity"

Visar resultat 11 - 15 av 20 avhandlingar innehållade orden striatal plasticity.

  1. 11. The functional organisation of basal ganglia inputs

    Författare :Yvonne Johansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The basal ganglia allow organisms to adjust their behaviour according to changes in their internal state or their environment. One essential prerequisite for the selection and execution of appropriate movements is the convergence of inputs from various sources, conveying sensory information, motor commands, reward value, and more. LÄS MER

  3. 12. Neuromodulation shapes interneuron communication in the mouse striatum

    Författare :Matthijs Constantijn Dorst; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : A proper understanding of cognition relies on detailed knowledge about the functional connectivity within and between brain areas. The striatum is generally regarded as the input structure to the basal ganglia, a group of subcortical nuclei that have been demonstrated to be involved in motor function and reward, amongst other functions. LÄS MER

  4. 13. Neuroplasticity and neurorestoration in the treatment of Parkinson's Disease: Experimental studies in the mouse

    Författare :Veronica Francardo; Basala gangliernas patofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Neuroplasticity is the brain´s capacity to respond to inner and outer challenges with functional and structural reorganizations. An aberrant activation of neuroplasticity pathways may contribute to the development of neurological disease. LÄS MER

  5. 14. Brain-derived neurotrophic factor in cerebral ischemia: a quantitative study on surviving and newly formed neurons

    Författare :Elin Gustafsson; Lund Klinisk fysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; brain-derived neurotrophic factor; cerebral ischemia; neuronal survival; neurogenesis; hippocampus; striatum; immunocytochemistry; stereology; neuropsykologi; Neurologi; neurophysiology; neuropsychology; neurofysiologi; Neurology;

    Sammanfattning : This study explores the role of brain-derived neurotrophic factor (BDNF) for neuronal vulnerability and neurogenesis following cerebral ischemia in the rat. Cerebral ischemia results in selective neuronal cell loss in specific brain regions. We here demonstrate the rank order of vulnerability in two regions affected by global forebrain ischemia, i. LÄS MER

  7. 15. Endogenous and treatment-induced neuroplasticity in mouse models of Parkinson's disease

    Författare :Francesco Bez; Basala gangliernas patofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Parkinson´s disease (PD) is an age-related neurodegenerative disorder characterized by a loss of nigral dopamine (DA) neurons that project their axons to the striatum. Striatal DA depletion causes the typical motor symptoms of PD. LÄS MER