Sökning: "streptococcal"
Visar resultat 1 - 5 av 93 avhandlingar innehållade ordet streptococcal.
1. Protein FOG at the interface between G streptococci and human host defence lines
Sammanfattning : Group G streptococci (GGS) may be of four different species and may infect humans and also animals. S. dysgalactiae equisimilis most commonly cause human GGS infections. These bacteria are part of the normal flora, but can cause pharyngitis, erysipelas and impetigo. LÄS MER
2. Recurrent Streptococcal Pharyngotonsillitis Studies on etiology and treatment
Sammanfattning : In acute pharyngotonsillitis group A streptococci (GAS) is the etiological agent in 30-50% of cases. Phenoxymethylpenicillin (pcV) is the drug of choice in Sweden. However, the failure rate is as high as 5-25% and further pcV treatment is followed by still higher failure rates. The background of failures remains largely elusive. LÄS MER
3. Streptococcal virulence and the coagulation system
Sammanfattning : This thesis explores streptococcal virulence from both mechanistic and evolutionary perspectives, where the mechanistic studies focus on interactions with the human coagulation system. We describe interactions between streptococcal surface proteins and components of the intrinsic pathway of coagulation and the kallikrein-kinin system in human plasma, as well as to how these surface proteins are produced in different growth phases. LÄS MER
4. The streptococcal IgG degrading enzyme IdeS : studies on host-pathogen interactions
Sammanfattning : The important human pathogen Streptococcus pyogenes causes both mild infections such as pharyngitis and impetigo but also severe life threatening invasive infections. Specific antibodies (IgG) recognize pathogens and are important mediators for pathogen clearance by the immune defence. S. LÄS MER
5. Molecular studies on streptococcal surface proteins
Sammanfattning : Streptococcus agalactiae and Streptococcus pyogenes are two related human pathogens causing different diseases. This thesis focuses on a number of surface proteins expressed by S. agalactiae and S. pyogenes and, more specifically, the molecular and biological characterization of these proteins. LÄS MER