Sökning: "streptococcal infections"

Visar resultat 21 - 25 av 50 avhandlingar innehållade orden streptococcal infections.

  1. 21. Signaling mechanisms in Streptococcal M1 proteininduced inflammation and injury in the lung

    Författare :Songen Zhang; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Streptococcus pyogenes of the M1 serotype is frequently associated with severe streptococcal infections. Acute lung injury is recognized as a key component in the pathophysiology of streptococcal M1 proteininduced inflammation. LÄS MER

  3. 22. On the effects of Streptococcal NAD+-glycohydrolase and Streptolysin O on macrophages

    Författare :Elsa Westerlund; Värd-patogeninteraktioner; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Innate immunity; macrophage; Streptococcus pyogenes; IL-1beta; Nad -glycohydrolase;

    Sammanfattning : SummaryThe human pathogen Streptococcus pyogenes (GAS) causes both superficial infections, such as strep throat, and invasive infections, such as necrotizing fasciitis, and is responsible for about half a million deaths each year. The number of GAS infections have increased since the 1980’s, due to the emergence of a M1T1 strain that has become widely disseminated. LÄS MER

  4. 23. Bacterial virulence or exorbitant host response? On innate immunity against the streptococcal M1 protein

    Författare :Sandra Persson; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skin infection; Streptococcus pyogenes; M1 protein; Innate Immunity; Host response; Virulence factor; Neutrophil recruitment; Heparin-binding protein HBP ; Leptospirosis;

    Sammanfattning : Bacterial infection is inevitable throughout a lifetime. What differs between mild andserious infections is the pathogen responsible and how the host immune systemresponds to it. A fundamental role to prevent infection is a proper physical barrier such as the skin and mucosa. LÄS MER

  5. 24. Induction and functional role of type I interferon in bacterial infection of macrophages

    Författare :Elin Movert; Infektionsimmunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; macrophage; Streptococcal M proteins; Mycobacterium marinum; Type I interferon; Infection;

    Sammanfattning : Infection represents an evolutionary arms race between pathogen and host. Thus, scientists find that pathogenic microbes have evolved elegant strategies to manipulate or avoid our immune system, allowing them to persist within the human population. LÄS MER

  7. 25. Molecular analysis of Streptococcus pyogenes and its interactions with the human host

    Författare :Andreas Berge; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; complement activation; fibrinogen; IgG; M protein; C5a peptidase; streptococcal cysteine proteinase; streptokinase; t-PA; Streptococcus pyogenes; plasminogen; C1q; insertional sequence.; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Streptococcus pyogenes causes infections only in humans, from trivial tonsillitis to life-threatening conditions. One of its most important virulence factors is the M-like protein family conferring resistance to phagocytosis to the bacterium. The M-like proteins are surface exposed rod-like molecules attached to the cell wall. Each strain of S. LÄS MER