Sökning: "strain-specificity"

Hittade 2 avhandlingar innehållade ordet strain-specificity.

  1. 1. Mechanisms of Antibiotic Resistance Evolution

    Författare :Michael Knopp; Dan Andersson; Anca Segall; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Antibiotic resistance evolution; Escherichia coli; Salmonella; porins; fitness; epistasis; strain-specificity; sub-MIC; de novo gene evolution;

    Sammanfattning : The continuing emergence and spread of antibiotic resistant bacteria are a threat to various applications in modern medicine and impose a strong economic burden on health systems. The development of new antibiotics is slow and cannot counterbalance the dissemination of resistant bacteria. LÄS MER

  2. 2. Virulence in Plasmodium falciparum malaria : mechanisms of PfEMP1-mediated rosetting

    Författare :Davide Angeletti; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Malaria is one of the most important infectious diseases in the world and the Plasmodium falciparum parasite is the causative agent of most of the severe cases. The pathogenesis of the disease is complex but sequestration and hence microvascular obstruction is associated with virulence of the parasite. LÄS MER