Sökning: "steroid hormones"

Visar resultat 21 - 25 av 120 avhandlingar innehållade orden steroid hormones.

  1. 21. Female sex hormones and health outcomes in women with specific focus on asthma

    Författare :Guo-Qiang Zhang; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; asthma; Bayesian estimation; case-control; causal inference; estrogens; female sex hormones; hormonal contraceptives; menarche; menopausal hormone therapy; menopause; meta-analysis; multiple imputation; progestogens; research reproducibility; robust variance estimation; systematic review; umbrella review; women;

    Sammanfattning : In humans, gender differences exist across a wide spectrum of diseases. For instance, women are more likely to develop Sjogren’s syndrome, systemic lupus erythematosus, and autoimmune thyroid disease compared to men. LÄS MER

  2. 22. Sex steroid effects on normal breast tissue

    Författare :Gunnar Söderqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Estrogen receptor; progesterone receptor; proliferation; breast epithelialcells; mammary epithelium; sulfatase; 17 HSD; regional differences; sex steroids;

    Sammanfattning : In Sweden, it is estimated that about one million women are treated with estrogen/progestogen for contraception and hormone replacement therapy (HRT). The possibility of an increased cancer risk in target organs has been vividly discussed for many years. LÄS MER

  3. 23. Exploring vitamin D and steroid hormone receptors – from healthy elderly to prostate cancer cells

    Författare :Maria Araceli Diaz Cruz; Maria Faresjö; Dennis Larsson Dennis Larsson; Johan Staaf; Jönköping University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; vitamin D; steroid hormone receptors; lifestyle; methylation; SNPs; healthy elderly; prostate cancer cells; crosstalk; PDIA3;

    Sammanfattning : The genetic background together with environmental factors and lifestyle are key contributors to the health of an individual. Genetic background is inherited and irreversible unless mutations occur. However, lifestyle habits (i.e. LÄS MER

  4. 24. Hormone concentrations during pregnancy and maternal risk of epithelial ovarian cancer

    Författare :Helena Schock; Eva Lundin; Annika Idahl; Renée Turzanski Fortner; Anne Zeleniuch-Jacquotte; Shelley S Tworoger; Umeå universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; epithelial ovarian cancer; sex steroid hormones; IGF-I; placental GH; AMH; pregnancy; prospective study; patologi; Pathology;

    Sammanfattning : Background: The aim of this thesis was to study the relationship of pre-diagnostic circulating concentrations of sex steroid hormones (androgens, estradiol, 17-hydroxyprogesterone, and progesterone), growth factors (insulin-like growth factor-I (IGF-I), placental growth hormone (GH)), sex hormone binding globulin (SHBG), and anti-Müllerian hormone (AMH) with risk of epithelial ovarian cancer (EOC) overall, and by tumor invasiveness and histology. A longitudinal study was used to assess patterns of hormonal changes during a single pregnancy, and in two consecutive pregnancies. LÄS MER

  5. 25. The hypertension-prone man: A study on the pathogenesis of hypertension with regard to insulin sensitivity

    Författare :Tomas Endre; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular system; sex steroid hormones; sodium retention; glycogen synthase; fibrinolysis; physical fitness; blood flow; insulin resistance; muscle fibres; Kardiovaskulära systemet;

    Sammanfattning : Hypertensive individuals, even non-obese, have been shown to be resistant to the insulin-mediated glucose uptake in peripheral tissues {mainly skeletal muscle}. The aim of this study was to investigate hypothetical pathophysiological mechanisms for the development of hypertension with regard to insulin sensitivity in normotensive men with a family history of hypertension (RELs) as compared to men with no such family history (CONs). LÄS MER