Sökning: "steric stabilisation"

Hittade 5 avhandlingar innehållade orden steric stabilisation.

  1. 1. Sterically stabilised liposomes and related lipid aggregates : Fundamental studies on aggragate structure and stability

    Författare :Markus Johnsson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physics; liposome; steric stabilisation; colloidal stability; cryo-TEM; drug delivery; Fysik; Physics; Fysik; Physical Chemistry; fysikalisk kemi;

    Sammanfattning : Various aspects of and approaches towards the steric stabilisation of liposomes have been investigated, mainly by use of fluorescence techniques and cryo-transmission electron microscopy (cryo-TEM). It is shown that PEG(2000)-lipids can be incorporated in the liposome membrane up to a critical concentration of 8-10 mol% without any observable structural perturbations. LÄS MER

  3. 2. Liposomes for Drug Delivery : from Physico-chemical Studies to Applications

    Författare :Nill Bergstrand; Katarina Edwards; Felix M Goni; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; liposome; steric stabilisation; BNCT; cryo-TEM; EGF; targeting; stability; permeability; pH-sensitive liposomes; triggered release; Fysikalisk kemi; Physical chemistry; Fysikalisk kemi; Physical Chemistry; fysikalisk kemi;

    Sammanfattning : Physico-chemical characterisation of structure and stability of liposomes intended for drug delivery is the central issue in this thesis. In addition, targeted liposomes to be used in boron neutron capture therapy (BNCT) were developed.Lysolipids and fatty acids are products formed upon hydrolysis of PC-lipids. LÄS MER

  4. 3. Intermediate State Stabilisation in Enzyme Catalysis Structural studies of two serine proteases and a photosynthetic reaction centre

    Författare :Gergely Katona; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; photosynthetic reaction centre; X-ray crystallography; structural mechanism; enzyme kinetics; serine protease; enzyme intermediate; enzyme catalysis;

    Sammanfattning : Enzymes play a key role in every organisms life. They catalyse chemical reactions and may also respond to external stimulus. The reoccurring theme of this thesis is how biologically relevant information can be gleaned from X-ray structures of the enzymes. LÄS MER

  5. 4. Structure and stability of liposomes : Interactions with micelle- forming surfactants

    Författare :Mats Silvander; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physics; Fysik; Physics; Fysik; Physical Chemistry; fysikalisk kemi;

    Sammanfattning : The stability of phospholipid lipomes interacting with micelle-forming surfactants was studied under physiological conditions (150 mM NaCl and pH=7.4 unless otherwise stated) mainly by use of cryo-TEM and fluorescence. LÄS MER

  7. 5. Theoretical Studies on CO2 Reduction Electrocatalysts

    Författare :Xiaoyu Chen; Mårten S. G. Ahlquist; Sandra Luber; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Computational Chemistry; CO2 reduction; electrocatalysis; Teoretisk kemi och biologi; Theoretical Chemistry and Biology;

    Sammanfattning : The atmospheric CO2 concentration has increased by more than 20% since 1980s and has now reached the highest level than at any point in the past 800 000 years. Electrochemical CO2 reductions are receiving particular in- terest as the apparatus are relatively easy to maintain and cheap to operate. LÄS MER