Sökning: "stereospecific"

Visar resultat 1 - 5 av 26 avhandlingar innehållade ordet stereospecific.

  1. 1. Direct Catalytic Nucleophilic Substitution of Non-Derivatized Alcohols

    Författare :Anon Bunrit; Joseph Samec; Joseph Moran; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; nucleophilic substitution; catalysis; alcohols; stereospecific; Lewis acid; Brønsted acid base; bifunctional; heterocycles; organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis focuses on the development of methods for the activation of the hydroxyl group in non-derivatized alcohols in substitution reactions. The thesis is divided into two parts, describing three different catalytic systems. LÄS MER

  3. 2. Stereospecific synthesis of β-D-fructofuranosides : synthesis of sucrose and structures related to plant and bacterial polysaccharides

    Författare :Fernando W. Sehgelmeble; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  4. 3. Development of methods for stereospecific synthesis of α- and β-D-fructofuranosides and β-D-glucuronic acid pyranosides and application of these methods in the assembly of bacterial polysaccharide structures

    Författare :Christian Krog-Jensen; Michael Bols; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi; Organic Chemistry; organisk kemi;

    Sammanfattning : .... LÄS MER

  5. 4. Pharmacokinetics of the enantiomers of thalidomide

    Författare :Tommy Eriksson; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein binding; blood distribution; stereoselective pharamacokinetics; pharmacokinetic modelling; oral administration; intravenous administration; chiral inversion; stereospecific assay; HPLC; Thalidomide; hydroxylated metabolites; enantiomers; in vitro kinetics; sedative effects; concentration-effect relationship.; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Sammanfattning : Thalidomide has a chiral center and the racemate of (+)-(R) and (-)-(S)-thalidomide was introduced as a hypnotic/sedative drug in 1957. In 1961 it was withdrawn due to teratogenicity and neuropathy. There is a growing interest in thalidomide treatment of immunomodulatory diseases. LÄS MER

  7. 5. Kinetic isotope effect studies of stereospecific and stereoselective 1,3-proton transfer in the indene system : methods, measurements, model calculations

    Författare :Olle Matsson; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER