Sökning: "stem group"
Visar resultat 11 - 15 av 205 avhandlingar innehållade orden stem group.
11. Stem cells for nerve repair and prevention of muscle atrophy
Sammanfattning : Peripheral nerve injury (PNI) is common and despite modern microsurgical techniques of repair, functional restoration is always incomplete. This results in impaired sensation and reduced motor function alongside pain and cold intolerance. LÄS MER
12. Ionic modulators of stem cell state
Sammanfattning : Tissue generation during development and maintenance throughout life relies on the proliferation and sequential specification of a group of cells. Stem cells are defined by the properties of self-renewal (division to produce daughter cells equipotent to the mother) and differentiation (division where at least one daughter is of a more restricted potential). LÄS MER
13. Salinomycin analogs : Mechanistic probes and structure–activity relationships against cancer stem cells
Sammanfattning : Cancer stem cells are a subpopulation of cells that possess an increased tumorigenic potential. Such cells are connected to drug resistance, metastasis, and cancer recurrence. In 2009, the polyether ionophore salinomycin was shown to exhibit selective activity against cancer stem cells. LÄS MER
14. Studies of the ABO and FORS Histo-Blood Group Systems: Focus on Flow Cytometric and Genetic Analysis
Sammanfattning : ABO is the clinically most important blood group system and its antigens are carbohydrate moieties present on the surface of the red blood cell (RBC) but also on other tissues throughout the body. The ABO gene encodes an enzyme, a glycosyltransferase (GT),that adds a terminal monosaccharide to the precursor structure, H antigen, to define the A or B antigens. LÄS MER
15. Novel Culture Strategies and Signal Transduction Pathways of Pluripotent Stem Cells
Sammanfattning : Pluripotent stem cells (PSCs) can self-renew indefinitely in culture while maintaining their capacity to differentiate into any cell type of an organism, thus offering novel sources for drug screening, in vitro disease modelling, and cell replacement therapies. However, due to their sensitive nature, many PSC lines are still cultured using undefined components such as serum or serum-derived components, on either feeder cells or complex protein mixes such as Matrigel or gelatine. LÄS MER