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Visar resultat 1 - 5 av 51 avhandlingar som matchar ovanstående sökkriterier.
1. Liver tissue characterization and influence of chemotherapy in liver surgery
Sammanfattning : Background & Aims: Primary liver cancer is the second most common cause of death from cancer worldwide. In the western world, the majority of liver malignancies consist of colorectal metastases. Liver resection is the primary treatment for cure in liver tumor disease. LÄS MER
2. Hepatitis C virus infection. Viral genotypes and factors promoting liver fibrosis
Sammanfattning : Hepatitis C virus (HCV) is associated with chronic infection in a majority of infected individuals. Chronic hepatitis C may result in liver cirrhosis or hepatocellular cancer and is therefore considered a major health problem worldwide. LÄS MER
3. Role of cholesterol metabolism in hepatic steatosis and glucose tolerance
Sammanfattning : The liver is the central organ for lipid, lipoprotein and glucose homeostasis, thus hepatic metabolic disturbances can predispose individuals to develop cardiometabolic disorders (CMD) such as atherosclerotic cardiovascular diseases (ASCVD), type 2 diabetes mellitus (T2DM), and nonalcoholic fatty liver disease (NAFLD).The overall aim of this thesis was to expand the knowledge on how genetic and pharmacological interventions on hepatic and intestinal cholesterol metabolism could affect the pathophysiology of CMD. LÄS MER
4. Ultrasound based shear wave elastography of the liver : a non-invasive method for evaluation of liver disease
Sammanfattning : Background: Detecting liver disease at an early stage is important, given that early intervention decreases the risk of developing cirrhosis and subsequently hepatocellular cancer (HCC). The non-invasive ultrasound-based shear wave elastography (SWE) has been used clinically for a decade to assess liver stiffness. LÄS MER
5. Berries in Prevention of Metabolic Disease – focus on obesity, diabetes and gut microbiota
Sammanfattning : The increasing prevalence of obesity is a worldwide health problem closely linked to diet and lifestyle factors. Obesity is associated with increased risk of several metabolic disorders including insulin resistance, nonalcoholic fatty liver disease and type 2 diabetes. LÄS MER