Sökning: "stearoyl-CoA desaturase"
Visar resultat 11 - 14 av 14 avhandlingar innehållade orden stearoyl-CoA desaturase.
11. Molecular mechanisms of antidiabetic effects of estrogen
Sammanfattning : The role of estrogen in the development and regulation of female reproduction is well established. However, recent studies demonstrate that estrogen has a multiple effects on body functions. At present, it is becoming well recognized that one of the important roles of estrogen is the maintenance of glucose homeostasis. LÄS MER
12. Molecular mechanisms of estrogen action in relation to metabolic disease
Sammanfattning : Estrogens have multiple effects on the body. Most studied are the effects on female reproduction. In this thesis, we have focused on the metabolic effects of estrogens. Estrogen treatment decreases adipose tissue mass and has anti-diabetic effects in humans and mice. LÄS MER
13. Targeting the ovary : mapping mechanisms to link endocrine-disrupting chemicals to female fertility
Sammanfattning : In recent decades, growing attention has been paid to endocrine-disrupting chemicals (EDCs) as mounting evidence suggests that they can cause detrimental reproductive outcomes in animals and humans. Even though epidemiological studies show the link between EDC exposure and adverse reproductive outcomes such as sub-fertility, longer time-to-pregnancy, and decreased ovarian reserve in women, the underlying mechanisms are not fully elucidated. LÄS MER
14. Identification and characterization of candidate genes for type 2 diabetes in the GK rat
Sammanfattning : Type 2 diabetes is a common multifactorial disorder with complex genetics, which presents with a heterogeneous clinical phenotype as a result of interaction between genetic susceptibility and environmental risk factors. Hence, the search for susceptibility genes for type 2 diabetes in man is difficult. LÄS MER
