Sökning: "stamcellstransplantation"

Hittade 4 avhandlingar innehållade ordet stamcellstransplantation.

  1. 1. Att genomgå stamcellstransplantation : Patienters uppfattning om och faktorer av betydelse för symptom, funktionellt status och hälsorelaterad livskvalitet

    Författare :Joacim Larsen; Karolinska Institutet; Karolinska Institutet; Stockholm Karolinska Institutet Huddinge Institutionen för laboratoriemedicin och Institutionen för medicin vid Karolinska Universitetssjukhuset vårdvetenskap och samhälle Sektionen för omvårdnad vid Institutionen för neurobiologi; []
    Nyckelord :livskvalitet; stamcellstransplantation;

    Sammanfattning : Stem-cell transplantation (SCT) is one therapy alternative in cases of malignant diseases. The SCT process begins with a course of high-dose chemotherapy with or without irradiation, which results in side-effects that can range from minimal to life-threatening. LÄS MER

  3. 2. Hematopoietic Stem Cell Transplantation for Treatment of Multiple Sclerosis in Sweden

    Författare :Christina Zjukovskaja; Joachim Burman; Kim Kultima; Susanna Brauner; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AHSCT; HSCT; hematopoietic stem cell transplantation; multiple sclerosis; RRMS; inflammation; biomarkers; АТГСК; ТГСК; Трансплантация гемопоэтических стволовых клеток; рассеянный склероз; воспаление; биомаркеры; AHSCT; HSCT; Hematopoetisk stamcellstransplantation; multipel skleros; RRMS; inflammation; biomarkör; Medicinsk vetenskap; Medical Science;

    Sammanfattning : This thesis investigated the efficacy and safety of autologous hematopoietic stem cell transplantation (AHSCT) as a treatment of multiple sclerosis. This thesis demonstrates that when compared to one of the most powerful disease-modifying drugs (DMDs), specifically alemtuzumab (ALZ), AHSCT is able to hold its ground. LÄS MER

  4. 3. Identification and Characterization of Stem Cells in Preleukemia and Leukemia

    Författare :Lars Nilsson; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Haematology; extracellulära vätskor; Hematologi; Philadelphia chromosome; acute lymphoblastic leukemia; polycytemia vera; 5q- syndrome; myelodysplastic syndromes; self-renewal; preleukemia; Hematopoietic stem cells; leukemic stem cells; extracellular fluids;

    Sammanfattning : Hematopoietic stem cells (HSCs) are responsible for the daily and life long production of large numbers of mature blood cells through highly regulated self-renewal and multilineage capabilities. Leukemias on the other hand, are characterized by a clonal, dysregulated, lineage skewed proliferation and impaired differentiation as the result of multiple accumulated genetic events. LÄS MER

  5. 4. SOX11 in Mantle Cell Lymphoma - Novel Tools for Diagnostic, Prognostic and Functional Investigations

    Författare :Lena Nordström; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antibodies; DNA methylation; Epigenetics; SOX11; Lymphoma;

    Sammanfattning : The goal of biomarker discovery is to identify disease defining molecules, which could be used to improve early detection and/or to predict survival and response to treatment. This thesis is about the transcription factor SOX11, a protein discovered in the context of mantle cell lymphoma in 2008, which shows great potential to be used as a clinical relevant biomarker. LÄS MER