Sökning: "spontaneous tone"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden spontaneous tone.

  1. 1. Regulation of spontaneous tone in guinea pig trachea

    Författare :Staffan Skogvall; Neurofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tetrodotoxin; lidocaine; substance P; tachykinin; prostaglandin; indomethacin; capsaicin; neuroepithelial endocrine cells; epithelium; oxygen; oscillations; spontaneous tone; Asthma; airway smooth muscle; electrical field stimulation.; Physiology; Fysiologi;

    Sammanfattning : Asthma is a common disease, characterized by periods of bronchoconstriction of unclear origin. This thesis examines a specific behavior of airway smooth muscle, the so-called spontaneous airway tone. It was suspected that a defect regulation of this tone may be a cause of asthmatic bronchoconstriction. LÄS MER

  3. 2. Prostaglandin E2 as mediator and modulator of airway smooth muscle responses

    Författare :Jesper Säfholm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Prostaglandin E2 (PGE2) is a lipid mediator produced by virtually every cell of the human body. Because common non-steroidal anti-inflammatory drugs (NSAIDs) inhibit its biosynthesis, PGE2 is usually considered to be a ‘pro-inflammatory’ mediator. The role of PGE2 in the lung and airways has however always been unclear. LÄS MER

  4. 3. Neuromuscular function in the normal and inflamed colon. An experimental study in rat

    Författare :Lars Börjesson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ATP; dextran sulphate sodium; DMPP; enteric nervous system; McN-A-343; nitric oxide; non-adrenergic; rat; second messenger; smooth muscle; VIP;

    Sammanfattning : Neuromuscular function of the longitudinal muscle layer of distal colon was investigated in segments from normal rats and from rats with colitis induced by dextran sulphate sodium (DSS) at 3% for 3 or 7 days or 5% for 7 days. The study was performed in vitro, on spontaneous tone, or after precontraction. LÄS MER

  5. 4. Adaptation to ischemia with special emphasis on nitric oxide

    Författare :Shinichi Tokuno; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Nitric oxide (NO) may play an essential role for maintenance of cardiac function and perfusion. Endothelial dysfunction of atherosclerotic vessels may aggravate cardiac ischemia/reperfusion injury. LÄS MER

  7. 5. Studies on inhibitory modulation of urinary tract motility

    Författare :Na Guan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Overactive Bladder (OAB) is a symptom syndrome characterized by urgency and frequency, with or without urge incontinence. Research concerning the mechanisms underlying OAB and finding new inhibitory factor(s) is intensive. LÄS MER