Sökning: "splice site"
Visar resultat 1 - 5 av 77 avhandlingar innehållade orden splice site.
1. Splice site selection in Saccharomyces cerevisiae pre-mRNA splicing
Sammanfattning : Pre-mRNA splicing is the process by which intervening sequences (introns) are removed from the coding sequences (exons) resulting in a mature messenger-RNA (mRNA). Splicing takes place in a large ribonucleoprotein complex termed the spliceosome, composed of several protein components and the five small nuclear RNAs (snRNAs) U I, U2, U4, U5 and U6. LÄS MER
2. Design and application of RNA therapeutics for splice site mutations
Sammanfattning : Precursor messenger RNA splicing is one of the most fundamental and complex mechanisms in eukaryotes. Over 90% of the human genes undergo alternative splicing, which is essential for the regulation of gene expression. A dynamic RNA-protein complex called the spliceosome catalyzes splicing. LÄS MER
3. Understanding the Noise : Spliceosomal snRNA Profiling
Sammanfattning : The concept of the gene has been constantly challenged by new discoveries in the life sciences. Recent challenging observations include the high frequency of alternative splicing events and the common transcription of non-protein-coding-RNAs (ncRNAs) from the genome. The latter has long been considered noise in biological systems. LÄS MER
4. Computational Approaches to the Identification and Characterization of Non-Coding RNA Genes
Sammanfattning : Non-coding RNAs (ncRNAs) have emerged as highly diverse and powerful key players in the cell, the range of capabilities spanning from catalyzing essential processes in all living organisms, e.g. protein synthesis, to being highly specific regulators of gene expression. LÄS MER
5. Regulation of alternative Pre-mRNA splicing : positive and negative control of adenovirus 3' splice site selection
Sammanfattning : .... LÄS MER