Sökning: "spindle assembly"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden spindle assembly.

  1. 1. Characterization of the inner nuclear membrane protein Samp1, during interphase and mitosis

    Författare :Veronica J. Larsson; Einar Hallberg; Katharine S. Ullman; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Samp1; LINC complex; nuclear lamina; MCLIP; nuclear envelope; spindle assembly; spindle stability; k-fiber; gamma tubulin; Aurora B; Haus6; Augmin; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : The nucleus, a hallmark in eukaryotic cells, contains the genome separating it from molecules in the cytoplasm. The nucleus is surrounded by a nuclear envelope consisting of two concentric membranes, the outer nuclear membrane and the inner nuclear membrane, the nuclear lamina and nuclear pore complexes. LÄS MER

  3. 2. Microtubule and spindle pole body regulation in the budding yeast mitotic spindle

    Författare :Marjan Abbasi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The microtubule organizing center (MTOC) is a specialized structure with a main function in microtubule (MT) nucleation and organization. In higher eukaryotes, the main MTOC is known as the centrosome, and its functional equivalent in yeast is the spindle pole body (SPB). LÄS MER

  4. 3. The roles of inner nuclear membrane proteins during interphase and mitosis

    Författare :Veronica J. Larsson; Einar Hallberg; Neus Visa; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Samp1; mitotic spindle; centrosome; LINC complex; Lamina; Sun1; mitosis; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : The nuclear envelope (NE) consists of two concentric membranes, the outer nuclear membrane (ONM) and the inner nuclear membrane (INM). The LINC (linker of nucleoskeleton and cytoskeleton) complex spans both the ONM and the INM connecting the cytoskeleton to the nucleoskeleton and chromatin. LÄS MER

  5. 4. Nuclear envelope protein interaction studies

    Författare :Mohammed Hakim Jaffer Ali; Einar Hallberg; Anki Östlund-Farrants; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Samp1; Nuclear envelope; protein interactions; chemical crosslinking; proteomics; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : The nuclear envelope (NE) separating the nucleoplasm from cytoplasm consists of two concentric lipid membranes, the outer (ONM) and inner (INM) nuclear membranes, the nuclear pore complexes (NPCs) and an underlying nuclear lamina network. The INM contains more than 100 unique transmembrane proteins of which only a few have been characterized. LÄS MER

  7. 5. Regulation of mitosis : molecular analysis of the anaphase-promoting complex

    Författare :Pia-Marie Jörgensen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :cell cycle; mitosis; anaphase; proteolysis; ubiquitination;

    Sammanfattning : Cell division is achieved by the progression through a series of events known as the cell cycle. To make sure that the original cell is copied with high fidelity, an elaborate control system using so called checkpoints is employed, preventing cell cycle events to occur prematurely or in the wrong order. LÄS MER