Sökning: "spinal cord ischaemia"
Hittade 3 avhandlingar innehållade orden spinal cord ischaemia.
1. Spinal cord oxygenation during thoracic aortic clamping in pigs
Sammanfattning : Despite a dramatic reduction in the mortality associated with thoracoabdominal aorticreplacement during the past 40 years, spinal cord ischaemia that results in paraplegia remainsa serious complication. Simple and reliable intraoperative monitoring techniques are neededto detect impending neurological deficit in time to prevent permanent damage. LÄS MER
2. Studies on sitting pressure and buttock microcirculation : aiming at developing an alarm in the prevention of pressure ulcers in patients with spinal cord injuries
Sammanfattning : Pressure ulcers in patients with spinal cord injuries are a major problem, the prevalence in this group being reported as high as 20 – 30 percent. Most pressure ulcers develop around the pelvic girdle, and the key-contributing factor in the development of pressure ulcers is ischaemia due to longstanding pressure. LÄS MER
3. Regulation of NMDA receptor properties by amino acids and cations : a biochemical and electrophysiological study
Sammanfattning : NMDA receptors are glutamate-regulated ion channels that are permeable to Ca2+, Na+ and K+ and are sensitive to voltage-dependent Mg2+-block. To investigate the modulatory effects of amino acids and cations on NMDA receptors and the possible regional differences in the pharmacology of NMDA receptors, I used mainly two techniques in this thesis: electrophysiological analysis of expressed NMDA receptors in Xenopusoocytes and biochemical receptor binding using [3H]MK-801 in membrane preparations from the rat cerebral cortex and spinal cord. LÄS MER