Sökning: "sphingosine-1-phosphate"

Visar resultat 11 - 12 av 12 avhandlingar innehållade ordet sphingosine-1-phosphate.

  1. 11. Regulatory importance of cyclic nucleotides in smooth muscle growth of the urogenital tract

    Författare :Per Adolfsson; Thoralf Christoffersen; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Smooth muscle hyperplasia/hypertrophy is, if not responsible for, so at least involved in those diseases, which impair life quality for most people in today's society.This thesis, presents a pharmacological investigation, related to the regulatory role of cyclic nucleotides, of smooth muscle hyperplasia/hypeitrophy in human uterine leiomyoma and benign prostate hyperplasia (BPH). LÄS MER

  3. 12. Regulation of p53 and susceptibility to cell death in chemically-induced preneoplastic hepatocytes

    Författare :Ilona Silins; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Induction of preneoplastic lesions, termed enzyme-altered foci (EAF), is considered to be an early step in the development of liver cancer. In view of the relatively homogenous properties of the majority of EAF, these lesions are suggested to arise as an adaptive response to toxic stress. LÄS MER