Sökning: "spheroid"
Visar resultat 16 - 20 av 39 avhandlingar innehållade ordet spheroid.
16. Angular dynamics of small particles in fluids
Sammanfattning : This thesis concerns the angular motion of small particles suspended in fluid flows. A small particle experiences a hydrodynamic torque due to the local fluid velocity, and this torque leads to rotational motion. When inertial effects are negligible the torque on an ellipsoidal particle is given by Jeffery's theory [Jeffery, G. B. LÄS MER
17. Precision medicine and targeted therapy : Turning the tables on cancer
Sammanfattning : An extended understanding of the molecular characteristics of cancer has led to a revolution within the field of precision medicine. This thesis explores the utilization of two targets for precision medicine, namely, CD44v6 and murine double-minute 2 and X (MDM2/X). LÄS MER
18. Molecular characterisation and prophylactic treatment strategies among women with benign gynecological disorders
Sammanfattning : Background: Female reproduction is controlled by hormones in a timed and well-coordinated manner by the hypothalamus- pituitary - ovarian axis. In response to the ovarian hormones such as estrogen, and progesterone, endometrium, the inner lining of the uterus, undergoes repeated cycles of tissue growth, differentiation, tissue shedding and remodelling. LÄS MER
19. Development of therapeutic strategies for quiescent tumor cell populations
Sammanfattning : Phenotypic screening is an effective approach to the discovery of small-molecule drugs. In this thesis, I have used cancer cells grown as 3D microtissues (multicellular spheroids) to study the effect of anticancer drugs and as drug discovery tools. LÄS MER
20. A Large Eddy Simulation Based Fluid-Structure Interaction Methodology with Application in Hydroelasticity
Sammanfattning : The phenomenon of hydroelasticity is a subarea of Fluid-Structure Interaction (FSI) and of major importance in many engineering applications related to hydrodynamics and naval architecture e.g. LÄS MER