Sökning: "spermatogenesis"

Visar resultat 1 - 5 av 47 avhandlingar innehållade ordet spermatogenesis.

  1. 1. The Xenopus tropicalis model for developmental endocrine and reproductive toxicity : Histological and molecular endpoints for disrupted spermatogenesis

    Författare :Sofie Svanholm; Cecilia Berg; Oskar Karlsson; Valérie Langlois; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Endocrine disrupting chemicals; Reproductive toxicology; Developmental toxicology; Spermatogenesis; Transgenerational; Xenopus tropicalis; Biology with specialization in Environmental Toxicology; Biologi med inriktning mot miljötoxikologi;

    Sammanfattning : Endocrine disrupting chemicals (EDCs) are linked to adverse effects in both humans and wildlife. There are however, large knowledge gaps regarding cause-effect and dose-response relationships between the interference with endocrine pathways and adverse effects in the organism, especially at puberty and in subsequent generations. LÄS MER

  3. 2. Growth factors in spermatogenesis

    Författare :Aida Wahlgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Testis; seminiferous tubules; proliferation; growth factors; sex steroids;

    Sammanfattning : The aim of this study was to increase the knowledge of die effects of locally produced growth factors and hormones on germ cell proliferation in rat testis in vitro. Since impaired sperm production and function accounts for half the cases of infertility, it is important to understand the physiological actions in germ cell development. LÄS MER

  4. 3. Mitochondrial Iron Metabolism : Study of mitoferrin in Drosophila melanogaster

    Författare :Christoph Metzendorf; Maria Lind Karlberg; Kenneth Söderhäll; Martina Muckenthaler; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; iron; Drosophila; mitochondria; mitoferrin; ferritin; spermatogenesis; cell cycle; DFO; MRS12; Cell and molecular biology; Cell- och molekylärbiologi; Biology with specialization in Comparative Physiology; Biologi med inriktning mot jämförande fysiologi;

    Sammanfattning : Iron has a dualistic character. On the one hand it is essential for the life of most organisms, on the other hand it is involved in the generation of reactive oxygen species that are implicated in diseases and aging. LÄS MER

  5. 4. Functional proteomics : Generation and analysis of cDNA-encoded proteins

    Författare :Susanne Gräslund; KTH; []
    Nyckelord :functional genomics; functional proteomics; gene characterization; E. coli expression; affinity purification; immunolocalization; mouse testis; spermatogenesis; rabbit antibodies; affibody; tektin; Anaphase-promoting complex or cyclosome.;

    Sammanfattning : .... LÄS MER

  7. 5. Hormone-Sensitive Lipase and Protein Kinase B; Molecular characterization in testis, adipose tissue and pancreatic beta cells

    Författare :Lena Stenson; Signaltransduktionsforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; signal transduction; pancreas; beta cells; adipocyte; insulin; Akt; protein kinase B; spermatogenesis; cholesterol esterase; hormone-sensitive lipase; testis; cAMP; Proteins; enzymology; Proteiner; enzymologi;

    Sammanfattning : Hormone-sensitive lipase (HSL) and protein kinase B (PKB) are enzymes that in different ways are associated with lipid metabolism. While HSL is the well-known lipolytic enzyme responsible for hydrolysis of stored triacylglycerols in adipose tissue, PKB is a recently identified serine/threonine protein kinase, ubiquitously expressed and involved in signal transduction pathways induced by insulin and growth factors. LÄS MER