Sökning: "specificity"

Visar resultat 11 - 15 av 1525 avhandlingar innehållade ordet specificity.

1. 11. Generation and evolution of human antibody repertoires

   Författare :Helena Persson; Institutionen för immunteknologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; specificity; Immunology; serology; transplantation; Immunologi; serologi; Biotechnology; Bioteknik; phage display; IgE; hapten; grass pollen allergen; diversity; antibody repertoire; antibody library; antibody evolution; affinity maturation; allergy;

   Sammanfattning : This thesis, which is based on five original papers, covers different aspects of antibody specificity and diversity, with the overall goal to understand the makeup of antibody repertoires and their functionality as they occur in vivo or as they are developed in the laboratory. Besides their importance in the adaptive immune response, antibodies have emerged as an invaluable tool in applications ranging from basic research to disease diagnostics and therapy. LÄS MER

3. 12. Engineering carbonic anhydrase for highly selective ester hydrolysis

   Författare :Gunnar Höst; Bengt-Harald Jonsson; Lars-Göran Mårtensson; Per Berglund; Linköpings universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; carbonic anhydrase; specificity; hydrolysis; rational design; protein engineering; plasmodium falciparum; Bioengineering; Bioteknik;

   Sammanfattning : I denna avhandling presenteras arbete utfört med enzymet humant karboanhydras II (HCAII). Enzymer är en typ av proteiner som accelererar (katalyserar) kemiska reaktioner, vilket är nödvändigt för allt levande. Den naturliga funktionen för HCAII är att katalysera omvandlingen av gasen koldioxid till vätekarbonat, som är löslig i vätska. LÄS MER

4. 13. The 14-3-3 protein family - Conserved structure, diverse functions

   Författare :Magnus Rosenquist; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; regulation; phosphorylation; plant; plasma membrane; fusicoccin; H ATPase; binding motifs; specificity; evolution; 14-3-3; isoforms; Plant biochemistry; Växtbiokemi;

   Sammanfattning : While once abstruse, 14-3-3 proteins are now well known as players in several cellular processes. These processes range from apoptosis and mitosis in mammals and yeast, to regulation of primary metabolism in plants. To date, 104 proteins have been shown to interact with 14-3-3s of which 85 are found in mammals and yeast, and 21 are found in plants. LÄS MER

5. 14. Prioritering vid utlarmning i prehospital vård

   Författare :Bosse Ek; Ulrica Nilsson; Birgitta Wireklint Sundström; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prioritization; experiences; triage; EMD; sensitivity; specificity; ambulance nurse; larmcentral; triage; ambulanssjukvård; innehållsanalys; sensitivitet; specificitet; Nursing Science; Vårdvetenskap;

   Sammanfattning : It is important that ambulances are urgently directed to patients who are in need of immediate help and of quick transportation to a hospital. Because resources are limited, emergency medical dispatch centres (EMD) cannot send ambulances with high priority to all callers. The efficiency of the system is therefore dependent on triage. LÄS MER

7. 15. Digital Electrical DNA Sensing

   Författare :Maoxiang Guo; Wouter van der Wijngaart; Fredrik Westerlund; KTH; []
   Nyckelord :DNA detection; thiol-ene-epoxy; rolling circle amplification; digital measurement; DNA stretching; microwell-array; gold nanowires; electrical measurement; specificity; limit of detection; liquid storage; disease diagnosis; lab-on-a-chip; point-of-care.;

   Sammanfattning : Molecule detection is a workhorse in life sciences and medicine, for example in cancer diagnosis and virus and bacterial detection. DNA analysis can provide vital information about the state of a host organism and its medical and health condition. LÄS MER