Sökning: "space-time clustering"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden space-time clustering.

  1. 1. Prognostic and epidemiological factors in childhood leukemia : studies of p53 and MDM2 expression and of space-time clustering

    Författare :Britt Gustafsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Childhood leukaemia; MDM2; p53; immunohistochemistry; non-Hodgkin s lymphomas; space-time clustering; viral hypothesis;

    Sammanfattning : Although cure rates in acute childhood leukaemias have improved it remains a challenge to understand how molecular aberrations influence the prognosis of leukaemia and thus the choice of optimal therapy. Some studies have suggested that dysfunction of the tumour suppressor gene p53 or the oncogene MDM2 could indicate disease progression in children with leukaemia. LÄS MER

  3. 2. Epidemiological studies including new methods for cluster analysis of acute childhood leukaemia and brain tumours in Sweden

    Författare :Ulf Hjalmars; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Epidemiology; childhood; leukaemia; brain tumours; geographical information systerns; cluster analysis; Scan statistic; Knox test; environmental factors;

    Sammanfattning : Background: The aetiology in childhood cancer is essentially unknown. Epidemiological investigations as to whether the incidence rates have changed for paediatric cancers or whether clustering of cases occur may give clues to possible causal factors. LÄS MER

  4. 3. Necrotising Enterocolitis : epidemiology and imaging

    Författare :Margareta Ahle; Roland Andersson; Peder Drott; Örjan Smedby; Hans Ringertz; Tomas Wester; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Necrotising enterocolitis (NEC) is a potentially devastating intestinal inflammation of multifactorial aetiology in premature or otherwise vulnerable neonates. Because of the broad spectrum of presentations, diagnosis and timing of surgical intervention may be challenging, and imaging needs to be an integrated part of management. LÄS MER

  5. 4. Necrotizing enterocolitis - growth, bone health and intestinal microbiota during childhood

    Författare :Amanda Magnusson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NEC; Prematur; Benhälsa; Tillväxt; Tarmflora;

    Sammanfattning : Necrotizing enterocolitis (NEC) is a dreaded gastrointestinal disease primarily affecting infants born preterm. Despite extensive research, NEC is still one of the most devastating diseases in neonatal intensive care. LÄS MER

  7. 5. Why do children get diabetes? : A study on some genetical, immunological and environmental factors

    Författare :Ulf Samuelsson; Hans Åkerblom; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Insulin dependent diabetes mellitus (IDDM) is one of the most common and serious chronic disorders of childhood. Despite advances in the knowledge about the cause of IDDM during the last decades the etiology still remains incompletely understood but is probably due to a complex network of genetic, immunological and environmental factors. LÄS MER