Sökning: "somatostatin"
Visar resultat 6 - 10 av 123 avhandlingar innehållade ordet somatostatin.
6. Pitfalls in β-cell ion imaging with fluorescent indicators and their use for real-time detection of somatostatin secretion
Sammanfattning : Fluorescent ion indicators have become indispensable tools in cell physiology. Dye indicators can easily be loaded into most types of cells, while genetically encoded indicators are advantageous in allowing specific cellular or subcellular targeting. LÄS MER
7. Physiology and Pathophysiology of Hormone Secretion from lslets of Langerhans
Sammanfattning : Diabetes is a metabolic disorder stemming from the improper regulation of blood glucose levels by hormones secreted by pancreatic islets of Langerhans. Paper I describes the mechanism by which glucose can regulate glucagon secretion, independent of membrane potential, from pancreatic α-cells, via modulation of endoplasmic reticulum Ca2+ handling. LÄS MER
8. Growth hormone regulation of hepatic drug-metabolising enzymes in humans and rats
Sammanfattning : There are pronounced sex-differences in the gene expression of several liver enzymes in the rat. The sex-differentiated secretion of growth hormone (GH) regulates these differences. We wanted to further investigate the mechanisms of this regulation in rats and to study the GH regulation of drug metabolism in man. LÄS MER
9. The Gastrin-ECL Cell Axis. Functional Aspects
Sammanfattning : The ECL cells constitute a prominent endocrine cell population in the acid-producing part of the stomach. They are controlled by circulating gastrin released from G-cells in the antrum. In response to gastrin, they secrete histamine, that in turn stimulates the parietal cell to secrete acid. LÄS MER
10. Origin, release and functional significance of the novel gastric hormone ghrelin
Sammanfattning : The novel gastric hormone ghrelin was discovered by virtue of its ability to release growth hormone (GH) via interaction with the so-called GH-secretagogue receptor (GHS-R). Earlier only synthetic agents were known to bind with the GHS-R, hence, ghrelin is the first identified endogenous ligand. LÄS MER