Sökning: "somatostatin receptors"
Visar resultat 21 - 25 av 44 avhandlingar innehållade orden somatostatin receptors.
21. Somatostatin, dendritic cells and peptide T in psoriasis : a clinical, immunohistochemical and functional study
Sammanfattning : Peptide T is an octapeptide designed to block the CD4 receptor. In a phase 1 study 9 psoriasis patients were treated with 2 mg peptide T i.v. once daily for 28 days and followed for a further 3 months. LÄS MER
22. Role of corticotropin-releasing factor, somatostatin and leptin in vagal nerve function and control of gastric emptying
Sammanfattning : The overall aim of this thesis was to study the effects of centrally acting CRF and leptin, and peripherally acting somatostatin on gastric emptying of glucose. Freely moving rats bearing chronic intragastric fistulas received intragastric infusions (1.0 ml/min) of glucose (12.5 % or 25 %) during 6-18 min. LÄS MER
23. Targeted radiotherapy in metastatic neuroendocrine tumours: clinical and experimental studies
Sammanfattning : ABSTRACT Neuroendocrine tumours (NET) often present at a metastatic stage, which diminishes the possibility for curative surgery. Peptide receptor radiotherapy (PRRT) with 177Lu-DOTATATE targets somatostatin receptors, which are overexpressed on NET cells. PRRT results in symptom relief and often tumour control of NETs, but rarely cure. LÄS MER
24. Leptin targets in the brain regulating body weight : receptors and down-stream mediators of leptin in neurons of the hypothalamus and brainstem
Sammanfattning : Obesity is a disease which has become a global epidemic that is beginning to replace undernutrition and infectious diseases as the most significant contributor to ill health in the world. In particular, obesity is associated with diabetes mellitus, hypertension and coronary heart disease. LÄS MER
25. On the neuropeptide mRNA expression following neuropsychopharmacological treatments
Sammanfattning : In addition to classical neurotransmitters, an increasing number of neuropeptides have been found in the brain. Although neuropeptides may play important roles especially in higher brain functions such as emotion, mood, memory, and learning, most focus has been directed upon classical neurotransmitters and their receptors. LÄS MER