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Visar resultat 1 - 5 av 6 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Identification of downstream targets of Alk signaling in Drosophila melanogaster

    Författare :Gaurav Varshney; Ruth Palmer; Udo Hacker; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drosophila; Alk; Jeb; visceral muscles; somatic muscles; Delilah; Goliath; Hand; Molecular biology; Molekylärbiologi;

    Sammanfattning : The Drosophila gene Anaplastic lymphoma kinase (Alk) is homologous to mammalian ALK, a member of the Alk/Ltk family of receptor tyrosine kinases. In Drosophila Alk is crucial for development of the embryonic visceral mesoderm, where it is the receptor for Jelly Belly (Jeb) ligand. LÄS MER

  2. 2. Midgut and muscle development in Drosophila melanogaster

    Författare :Margret Shirinian; Ruth Palmer; Anne Uve; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drosophila; visceral mesoderm; endoderm; somatic muscles; Alk; C3G; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The fully developed and functional Drosophila midgut comprises two layers, the visceral mesoderm and the endoderm. The visceral muscle of the midgut is formed by the fusion of founder cells with fusion competent cells to form the muscle syncytia. LÄS MER

  3. 3. Allocation of body resources to reproduction in butterflies

    Författare :Fredrik Stjernholm; Bengt Karlsson; Christer Wiklund; Jane K. Hill; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; Zoology; Ecology; Butterflies; Reproduction; Life histories; Trade-offs; Resource use; Terrestrial; freshwater and marine ecology; Terrestisk; limnisk och marin ekologi;

    Sammanfattning : The life-history of an organism can be studied and understood in terms of acquisition and expenditure of resources. In butterflies, the use of resources for reproduction has been the focus of much research due to the possibility to easily quantify both the input of resources from different sources over the life-cycle as well as the partitioning of these resources to reproduction. LÄS MER

  4. 4. Deciphering the Alk signaling pathway in Drosophila

    Författare :Fredrik Hugosson; Ruth H. Palmer; Osamu Shimmi; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drosophila; Alk; RTK; visceral mesoderm; signal transduction; growth factor; transcription factor; molekylärbiologi; Molecular Biology;

    Sammanfattning : In Drosophila melanogaster the visceral mesoderm (VM) develops during embryogenesis in a process where myoblasts become specified to generate two distinct cell types, the founder cells (FCs) and the fusion competent myoblasts (FCMs) that consequently fuses. The cell specification is dependent on cell signaling mediated by the receptor tyrosine kinase (RTK) Anaplastic lymphoma kinase (Alk) and its ligand Jelly belly (Jeb), how this further sets up different identity programs that drive myoblasts to differentiate into FCs and FCMs is still not well understood. LÄS MER

  5. 5. Neural circuits engaged in mastication and orofacial nociception

    Författare :Tuija Athanassiadis; K-G Westberg; Sten Grillner; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rhythmical jaw movements; central pattern generator; trigeminal system; rabbit; Rat; c-Fos; nociceptors; muscle pain; muscle spindle afferents; glutamate; Neurophysiology; Neurofysiologi; fysiologi; Physiology;

    Sammanfattning : A deeper understanding of both movement control and the effects of nociceptor inputs on our motor systems is critical for proper clinical diagnosis of musculo-skeletal dysfunctions and for development of novel rehabilitation schemes. In the jaw system, masticatory movements are produced by a central pattern generator (CPG) located in the brainstem. LÄS MER