Sökning: "somatic copy number alteration"

Hittade 2 avhandlingar innehållade orden somatic copy number alteration.

  1. 1. Profiling of Small Intestine Neuroendocrine Tumors

    Författare :Ellinor Andersson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; small intestine neuroendocrine tumor; somatic copy number alteration; expression profiling; APLP1; survival; targeted therapy;

    Sammanfattning : Small intestine neuroendocrine tumors (SI-NETs) are malignant neoplasms usually presenting with disseminated disease and symptoms of hormone overproduction. Radical surgery is curative but can only be performed for localized disease. For most patients the disease follows a progressive and fatal course. LÄS MER

  3. 2. Genetic and epigenetic mechanisms in primary hyperparathyroidism

    Författare :Luqman Sulaiman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Primary hyperparathyroidism (PHPT) is a common endocrine disorder characterized by abnormally excessive secretion of parathyroid hormone (PTH) and elevated serum calcium. PHPT patients can develop a wide range of complications affecting many body organs such as the skeleton, kidneys and heart. LÄS MER