Sökning: "solution conformational analysis"

Visar resultat 16 - 20 av 31 avhandlingar innehållade orden solution conformational analysis.

1. 16. Conformational Dynamics of Rhodopsins Visualized by Time-resolved Wide Angle X-ray Scattering

   Författare :Erik Malmerberg; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Time-resolved wide Angle X-ray Scattering; Retinylidene proteins; Rhodopsin; Bacteriorhodopsin; Proteorhodopsin;

   Sammanfattning : Rhodopsins are a family of light-sensitive proteins found in the cellular membranes of a wide range of living organisms. These membrane proteins share a common molecular architecture and are able to use light energy to perform a variety of different biological functions. LÄS MER

3. 17. Time-resolved X-ray diffraction and solution scattering studies of Sensory Rhodopsin II in isolation and in complex with its transducer

   Författare :Giorgia Ortolani; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; light-activated membrane protein; microbial Rhodopsins; Sensory rhodopsin II; SRII; SRII:HtrII; transducer; SSX; XSS; time-resolved;

   Sammanfattning : Light is an important source of energy for many living organisms. Many life forms have therefore evolved cellular receptors that are able to sense light and thereby optimise conditions for photosynthesis and pho- totrophy. LÄS MER

4. 18. Single molecule dynamics

   Författare :Lars Edman; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Properties found in an ensemble of molecules may not be understood if it is not possible to study each molecule one by one. This thesis is concerned with the study of the dynamic properties of individual complex biological molecules as observed by confocal single-molecule fluorescence spectroscopy. LÄS MER

5. 19. Characterising Halogen Bonding in a Cooperative Model System

   Författare :Stefan Peintner; Mate Erdelyi; Anja Sandström; Uppsala universitet; []
   Nyckelord :Halogen Bond; NMR; peptide; conformation; RDC; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi;

   Sammanfattning : Non-covalent interactions are the main driving factor for secondary structure formation of biomacromolecules and are of enormous importance for the direction of molecular recognition events, for example those of importance for drug discovery. Profound understanding of these interactions is of vital importance to achieve high affinity and selectivity of a ligand to a chosen target. LÄS MER

7. 20. Poly(N-Isopropylacrylamide) Polymer Brush Functionalized Nanostructures as Thermo-Responsive Gating Systems for Protein Transportation

   Författare :Justas Svirelis; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; biomolecule transportation; Poly N-Isopropylacrylamide ; polymer brushes; fluorescence microscopy; thermo-responsive polymers; surface plasmon resonance;

   Sammanfattning : Controlling molecule translocation through nanosized gaps is of great interest in novel systems for single molecule analysis and biomolecular membranes. The molecular gating property of thermo-responsive end-grafted poly(N-isopropylacrylamide) (PNIPAM) polymer brushes on well-shaped gold-silica nanostructures is intended to be investigated for controlled protein transportation via extinction spectroscopy and fluorescence microscopy methods below and above PNIPAM lower critical solution temperature (LCST; 32 °C in water). LÄS MER