Sökning: "solute-membrane interactions"

Hittade 2 avhandlingar innehållade orden solute-membrane interactions.

  1. 1. Computer Simulations of Heterogenous Biomembranes

    Författare :Joakim P. M. Jämbeck; Alexander P. Lyubartsev; D. Peter Tieleman; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular simulation; force field development; biological membranes; free energy calculations; rational drug design; solute-membrane interactions; fysikalisk kemi; Physical Chemistry;

    Sammanfattning : Molecular modeling has come a long way during the past decades and in the current thesis modeling of biological membranes is the focus. The main method of choice has been classical Molecular Dynamics simulations and for this technique a model Hamiltonian, or force field (FF), has been developed for lipids to be used for biological membranes. LÄS MER

  3. 2. Chromatographic studies of interactions between solutes, lipid bilayers and the glucose transporter Glut1

    Författare :Yanxiao Zhang; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Biokemi; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : It is advantageous to analyze solute interactions with biological membranes by chromatography on stationary phases that mimic the membrane structures. In the present work, liposomes, proteoliposomes, human red cells and red cell membrane vesicles were immobilized for analyses ofinteractions between solutes (peptides, drugs, inhibitors and glucose), lipid bilayers and theglucose transporter Glut1. LÄS MER