Sökning: "soluble transferrin receptor"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden soluble transferrin receptor.

  1. 1. The dynamics of red blood cells and iron status during infancy

    Författare :Marie Larsson; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Barnreferensintervall; Röda blodkroppar; Erytrocyter; Extremt för tidig födsel; Erytropoes; Klinisk kemi; Järnstatus; Ferritin; sTfR; Neonatologi; Pediatrik; Fetal tillväxthämning; Referensintervall; Pediatric reference intervals; Reference limits; Extremely preterm birth; Fetal growth restriction; Clinical chemistry; Iron status; Red blood cells; Erythrocyte; Transfusion; Ferritin; sTfR; Hemoglobin; Neonatal; Reference intervals; Umbilical cord blood; Infancy; Iron deficiency; Anemia; Acute phase response; soluble Transferrin receptor; Neonatal intensive care; Erythropoiesis; Birth; Infant;

    Sammanfattning : Red blood cell (RBC) and iron status biomarkers are commonly used in clinical diagnostics. However, interpretations of infant test results are inherently challenging. LÄS MER

  2. 2. Enhancing the therapeutic effect of biological drugs with protein engineering : Focusing on pre-clinical Alzheimer’s disease therapy

    Författare :Fadi Rofo; Greta Hultqvist; Stina Syvänen; Sara Mangsbo; Joy Zuchero; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; amyloid-beta; blood-brain barrier; transferrin receptor; protein-drugs; multivalent-bispecific antibodies;

    Sammanfattning : Aggregation of the amyloid-β peptide (Aβ) is one of the main pathological hallmarks in Alzheimer’s disease (AD). The soluble Aβ aggregates (oligomers and protofibrils) have shown to be the most harmful species. Hence, targeting these aggregates can be of therapeutic potential. LÄS MER

  3. 3. Cadmium exposure and iron status

    Författare :Agneta Åkesson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :environmental exposure; biological monitoring; bioavailability; pregnancy; cadmium; iron deficiency; hemochromatosis; dietary intake; soluble transferrin receptor; serum ferritin;

    Sammanfattning : People are exposed to cadmium, a ubiquitous toxic metal, mainly via basic foods such as cereals and vegetables. Cadmium accumulates in the kidney, and renal tubular damage is considered the critical effect. Recently, association with osteoporosis at environmental exposure levels was indicated. LÄS MER

  4. 4. Preclinical PET imaging of Alzheimer's disease progression

    Författare :Xiaotian T. Fang; Stina Syvänen; Dag Sehlin; Lars Lannfelt; Merja Haaparanta-Solin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; transgenic mice; PET; antibody-based tracer; mGluR5; ABP688; di-scFv; amyloid-β;

    Sammanfattning : Amyloid PET imaging with [11C]PIB enabled detection of Aβ for the first time in vivo. However, [11C]PIB is a small molecule that binds only the insoluble Aβ plaque. Rather, the soluble Aβ aggregates are considered the cause of Alzheimer’s disease (AD). LÄS MER

  5. 5. Iron deficiency in female adolescent athletes - prevalence, mechanisms and diagnostics

    Författare :Göran Sandström; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; iron deficiency; iron deficiency anaemia; female adolescents; physical activity; inflammation; Helicobacter pylori;

    Sammanfattning : Background: Iron deficiency (ID) is a very common condition and the most common nutritional deficiency in the world. ID mostly affects females, both athletes and non-athletes. Several underlying mechanisms are identified such as insufficient dietary intake and losses by menses. LÄS MER