Sökning: "soluble immune markers"

Visar resultat 21 - 25 av 42 avhandlingar innehållade orden soluble immune markers.

  1. 21. The role of granulocyte antibodies in monocyte and granulocyte activation

    Författare :Agneta Wikman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :ANCA; adhesion molecules; CD11b; CD62L; granulocyte antibodies; granulocytes; monocytes; systemic vasculitis;

    Sammanfattning : Granulocytes and monocytes are important cells during the first phase of inflammation. They are activated and recruited from the blood vessels to inflammatory sites via the regulation of receptors involved in adhesion to endothelium. LÄS MER

  3. 22. T Regulatory Cells – Friends or Foes?

    Författare :Camilla Lindqvist; Angelica Loskog; Thomas Tötterman; Vivianne Malmström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Treg; T regulatory cell; FoxP3; CD25; CLL; B-cell lymphoma; Clinical immunology; Klinisk immunologi; Klinisk immunologi; Clinical Immunology;

    Sammanfattning : T regulatory cells (Tregs) have been extensively studied in patients with cancer or autoimmunity. These cells hamper the immune system’s ability to clear tumor cells in cancer patients. In autoimmune diseases, on the other hand, they are not able to restrain autoreactive immune responses. LÄS MER

  4. 23. The role of microbial translocation and gut microbiota in HIV-1 infection

    Författare :Jan Vesterbacka; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : HIV-1 infection is characterized by persistent systemic inflammation and immune activation, even in patients receiving effective antiretroviral therapy (ART). Translocation of microbial compounds from a leaky gut to systemic circulation, so called microbial translocation (MT), is a major driver of the immune activation. LÄS MER

  5. 24. Pathogenetic factors of importance for the development and progression of rheumatoid arthritis

    Författare :Heidi Kokkonen; Solbritt Rantapää-Dahlqvist; Dirkjan van Schaardenburg; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatoid arthritis; cytokines; autoantibodies; isotypes; PTPN22; HLA-SE; reumatologi; rheumatology;

    Sammanfattning : Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint inflammation eventually leading to the destruction of cartilage and bone. The aetiopathogenesis is not completely understood, but previous studies have shown that the disease is multifactorial with genetic, environmental and hormonal factors involved. Immune cells, e. LÄS MER

  7. 25. B cell fate following immunization : from memory B cells to plasma cells

    Författare :Paola Martínez Murillo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Most approved successful human vaccines induce neutralizing antibody titers maintained above a given threshold for long-term protection against potential pathogen exposure. The pathogens targeted by these vaccines are antigenically stable and the relevant epitopes are immunogenic. LÄS MER