Sökning: "soluble immune markers"

Visar resultat 16 - 20 av 42 avhandlingar innehållade orden soluble immune markers.

  1. 16. CTLA-4 expression, regulation and associations in autoimmune myasthenia gravis

    Författare :XiongBiao Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cytotoxic-T-lymphocyte-associated antigen 4 CTLA-4 ; Myasthenia gravis MG ; Immune inhibitory receptor; Autoimmune disease; Genetic polymorphism.;

    Sammanfattning : Myasthenia gravis (MG) is a neuromuscular disease with muscle weakness due to an autoimmune attack against the nicotinic acetylcholine receptor (nAChR) on the skeletal muscle endplate. Cytotoxic-T-lymphocyte-associated antigen 4 (CTLA-4) plays a global inhibitory role in the immune system and has a crucial role in autoimmunity. LÄS MER

  3. 17. Detection of apoptosis in patients with coronary artery disease : Assessment of temporal patterns and potential sources

    Författare :Aleksander Szymanowski; Lennart Nilsson; Lena Jonasson; Eva Swahn; Stefan Jovinge; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The atherosclerotic process and its consequences are considered driven by an imbalance between pro- and ant-inflammatory actions. One contributing factor in this scenario is an altered regulation of apoptosis, which affects both immune, vascular and myocardial cells. LÄS MER

  4. 18. Uniquely NK cells : the multifaceted roles of the natural killers

    Författare :Shiyong Neo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Natural killer cells (NK cells) were primarily discovered through the study of tumor cell recognition during immune surveillance. Till date, many studies had characterized NK cells to have immune regulatory roles in both physiological and pathological context. LÄS MER

  5. 19. Studies of the Systemic Inflammation in Psoriasis

    Författare :Gunnthorunn Sigurdardottir; Charlotta Enerbäck; Cecilia Bivik; Ingrid Synnerstad; Maria Bradley; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Psoriasis is a common immune-mediated disease, where an increased prevalence of extra cutaneous diseases and mortality is observed. Common inflammatory mechanisms are implicated. LÄS MER

  7. 20. Exosomes : immunomodulators in cancer and therapy

    Författare :Stefanie Hiltbrunner; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Exosomes are nano-sized membrane vesicles derived from the late endosomal compartment. They are capable of transferring proteins, lipids and RNA between cells. B cell and dendritic cell (DC)-derived exosomes express major histocompatibility complex (MHC) class I and II, as well as costimulatory molecules (CD80/86) and can initiate T cell responses. LÄS MER