Avancerad sökning

Visar resultat 1 - 5 av 42 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Aspects on sepsis : treatment and markers

    Författare :Anna Gustafsson; Malmö högskola; []
    Nyckelord :antimicrobial peptides; cytokines; lipoteichoic acid; lipopolysaccharide; soluble urokinase plasminogen activator receptor; sepsis;

    Sammanfattning : Sepsis is one of the greatest challenges in critical care medicine today, while the treatment of sepsis and evaluation of its severity is complicated. The first part of this thesis presents two approaches on the use of antimicrobial peptides in sepsis treatment, relying on both soluble and immobilized peptides. LÄS MER

  3. 2. Pinpointing biomarkers of importance for children with combined type 1 diabetes and celiac disease

    Författare :Andrea Tompa; Maria Faresjö; Karin Åkesson; Mikael Karlsson; Jönköping University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; celiac disease; children; biomarkers; immune markers; flow cytometry; cryopreservation; T cells; T-regulatory cells; B cells; B-regulatory cells; cytokines; chemokines; acute phase proteins; adipocytokines; matrix metalloproteinases;

    Sammanfattning : Type 1 diabetes (T1D) and celiac disease are both characterized by an autoimmune feature. The diseases also share the same risk genes, and thereby patients have an increased risk of developing the other disease subsequently. LÄS MER

  4. 3. HIV-1 evolution, disease progression and molecular epidemiology of HIV-1 single and HIV-1 and HIV-2 dual-infected individuals in Guinea-Bissau

    Författare :Joakim Esbjörnsson; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; HIV-2; Guinea-Bissau; subtype; disease progression; evolution; coreceptor tropism; CXCR4; gp120; V1-V3; CD4%; CD8%; soluble immune markers;

    Sammanfattning : The two genetically related human lentiviruses known today, HIV-1 (which is pandemic) and HIV-2 (which mainly is confined to West Africa), are the causative agents of AIDS. Progressive immune dysfunction and AIDS develop in most cases of untreated HIV-1 infection, but only in approximately 25-30% of HIV-2 infected individuals. LÄS MER

  5. 4. SLPI and soluble BTLA as immunological markers in severe bacterial infections

    Författare :Anna Lange; Olof Hultgren; Jonas Sundén-Cullberg; Peter Bergman; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SLPI; sBTLA; sepsis; bloodstream infection; pneumonia;

    Sammanfattning : Clinical presentation, and outcome of infections are affected by host-, and etiology- (focus of infection and pathogen) related factors. The immune response is controlled by a network of regulating pathways. LÄS MER

  7. 5. Immune mediators in people with HIV and tuberculosis

    Författare :Oskar Olsson; Klinisk infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Tuberculosis (TB) is the most common cause of death among people with HIV (PWH). PWH often have atypical clinical manifestations of TB, and TB disease can therefore be missed. Better screening markers could identify individuals with high likelihood of TB disease. LÄS MER