Sökning: "soluble carriers"

Visar resultat 1 - 5 av 23 avhandlingar innehållade orden soluble carriers.

1. 1. Characterization of conjugated protease inhibitors

   Författare :Erika Billinger; Gunnar Johansson; Boris Turk; Uppsala universitet; []
   Nyckelord :Serine protease inhibitors; conjugation; immobilization; leupeptin analogues; potato serine protease inhibitor; soluble carriers; inorganic carriers.; Biokemi; Biochemistry;

   Sammanfattning : The overall theme of this thesis is a step by step approach for the design and characterization of conjugated protease inhibitors. This involves both a new assay method for protease activity and protease inhibition (paper I), a study of the stoichiometry for protease inhibitor interaction (paper II), design of inhibitory peptides (paper IV) and the construction of inhibitor conjugates (paper III & IV). LÄS MER

3. 2. Factor V Leiden mutation and pregnancy. Haemostasis during pregnancy in non-carriers and carriers of factor V Leiden mutation, with special emphasis on placenta-mediated and venous thromboembolic complications and on blood coagulation and fibrinolysis markers for prediction of complications

   Författare :Ulla Kjellberg; Göteborgs universitet; []
   Nyckelord :Activated protein C; D-dimer; Factor V Leiden; fibrinolysis; haemostasis; obstetric complications; platelet function; pregnancy; prothrombin fragment 1 2; soluble fibrin; Sonoclot; thrombosis;

   Sammanfattning : Factor V Leiden (FVL) mutation elevates the risk of venous thromboembolism (VTE) in general. During pregnancy, the haemostatic balance is changed in the direction of hypercoagulability, resulting in an increased incidence of VTE. 42 women were followed longitudinally during pregnancy and the puerperium. LÄS MER

4. 3. c Cytochromes as Electron Carriers in Microbial Chlorate Respiration

   Författare :Anna Smedja Bäcklund; Thomas Nilsson; Pia Ädelroth; Karlstads universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; c cytochrome; chlorate reduction; electron transport; Biochemistry; Biokemi; Kemi; Chemistry;

   Sammanfattning : Microbial respiration of oxochlorates is important for the biotreatment of effluents from industries where oxochlorates are produced or handled. Several bacterial species are capable to use perchlorate and/or chlorate as an alternative electron acceptor in absence of oxygen. LÄS MER

5. 4. Amyloid [beta]-peptide and tau in the diagnosis and pathogenesis of Alzheimer's disease

   Författare :Malene Jensen; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Alzheimer's disease (AD) is a devastating disorder, for which no cure yet has been found. The search pathogenic mechanisms and early diagnostic markers of the disease is in the focus of today's research. LÄS MER

7. 5. Regulation of TNF-alpha : implications for health and disease

   Författare :Tiina Skoog; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Adhesion molecules; adipocyte; atherosclerosis; DNase I HS site; EMSA; IMT; polymorphism; TNF-alpha;

   Sammanfattning : Tumor necrosis factor-alpha (TNF-alpha) is a proinflammatory cytokine, which is implicated in some metabolic disorders and may play a role in the development of cardiovascular disease. When healthy 50-year-old men were studied, the plasma TNF-alpha concentration was associated with systolic and diastolic blood pressure, degree of alimentary lipaemia, plasma VLDL triglyceride and LDL cholesterol concentrations, peak LDL particle size and all measured cell adhesion molecules. LÄS MER