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1. 1. Dopachrome and aminochrome, the oxidized metabolites of dopa and dopamine : studies on the molecular mechanisms underlying their reduction and conjugation with glutathione

   Författare :Sofia Baez; Francisco Solano Munoz; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

   Sammanfattning : Dopamine, like other catecholamines can be oxidized to the corresponding ortho-quinone, which undergoes cyclization of its amino chain to cyclized dopamine ortho-quinone (aminochrome). Both o-quinones are toxic metabolites that may contribute to neurotoxic effects of these catecholamines. LÄS MER