Sökning: "smooth muscle cells"

Visar resultat 11 - 15 av 249 avhandlingar innehållade orden smooth muscle cells.

  1. 11. Mechanisms of stretch-induced growth and contractile differentiation in vascular smooth muscle

    Detta är en avhandling från Asad Zeidan

    Författare :Asad Zeidan; [2003]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Fysiologi; Physiology; SM22a; ERK1 2; caveolae; stretch; Smooth muscle; differentiation;

    Sammanfattning : Vascular smooth muscle can adapt to increased intraluminal pressure by remodelling and hypertrophy, as seen in hypertension. The molecular mechanisms responsible for this are still incompletely characterized. LÄS MER

  2. 12. PACAP and airway regulation with special reference to smooth muscle and neutrophils

    Detta är en avhandling från Department of Otorhinolaryngology, Lund University

    Författare :Johan Kinhult; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; audiology; auditive system and speech; Otorinolaryngologi; audiologi; hörsel- och talorganen; Otorhinolaryngology; allergy; neutrophils; smooth muscle; PACAP; airway regulation;

    Sammanfattning : The investigations focus on the neuropeptidepituitary adenylate cyclase-activating peptide and its effects on airway regulation, with emphasis on smooth muscle relaxation and neutrophil activation and migration. In the nasal mucosa, PACAP-containing nerve fibers were localized invascular smooth muscle and close to seromucous glands. LÄS MER

  3. 13. Inducible nitric oxide synthase : in vascular smooth muscle cells

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Medicine

    Författare :Zhong-qun Yan; Karolinska Institutet.; Karolinska Institutet.; [1998]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nitric oxide; nitric oxide synthase; vascular smooth muscle cells; transcriptional regulation; NF-[kappa]B; I[kappa]B; pathophysiological role;

    Sammanfattning : Besides the constitutively expressed nitric oxide synthase (NOS) in endothelial cells, vascular smooth muscle cells (SMC) have the potential to express the inducible isoform of NOS (iNOS). Given the important effects of nitric oxide and the high output of this enzyme, expression of iNOS in SMC and its pathophysiological significance were investigated in the present study. LÄS MER

  4. 14. Role of NFAT (nuclear factor of activated T cells) in vascular smooth muscle

    Detta är en avhandling från Department of Clinical Sciences, Lund University

    Författare :Lisa Berglund; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vascular smooth muscle; proliferation; A-285222; osteopontin; AIF-1; diabetes; vascular disease; calcium; glucose; NFAT;

    Sammanfattning : The calcium-dependent transcription factor NFAT was first described as a key player in immune cell regulation. Since then, NFAT signaling has been shown to be crucial for normal vascular development during embryogenesis. LÄS MER

  5. 15. A genomic approach to smooth muscle differentiation and diversity

    Detta är en avhandling från Department of Clinical Sciences, Lund University

    Författare :Sven Nelander; Göteborgs universitet.; Gothenburg University.; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Keywords: smooth muscle; phenotype; transcriptional regulation; differentiation; transcriptome; microarray; computational prediction; co-expression network; regulatory sequence analysis; gene module; gene battery;

    Sammanfattning : Smooth muscle cells (SMCs) are a broad class of contractile cells that are found in a number of organs systems, including the vasculature, the urogenital system, the bronchi and the gastrointestinal tract. The two main functions exerted by SMCs are to provide contractile force and to synthesize structural components of the extracellular matrix. LÄS MER