Sökning: "small molecule donors"

Visar resultat 6 - 10 av 13 avhandlingar innehållade orden small molecule donors.

  1. 6. Targeting polo-like kinase 1 in pediatric leukemia

    Författare :Oksana Goroshchuk; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Acute lymphoblastic leukemia (ALL) is one of the most common cancers among children in the world, with almost 90% complete remission rate after the primary treatment. However, some patients are resistant to treatment and some relapse later. Moreover, existing treatments are toxic and induce life-long adverse effects. LÄS MER

  3. 7. Intestinal preservation for transplantation: translational approaches

    Författare :John M. Söfteland; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intestinal transplantation; intestinal preservation; apoptosis; tight junction; luminal preservation;

    Sammanfattning : Background: Intestinal preservation injury (IPI) may result in various degrees of mucosal damage, which may later favor bacterial translocation, post-reperfusion syndrome, and upregulation of alloreactivity. Experimental evidence suggests that combining vascular perfusion and cold storage with luminal interventions using polyethylene glycol (PEG) solutions may mitigate the mucosal damage and extend the safe storage time. LÄS MER

  4. 8. Human cytomegalovirus (HCMV) : detection and elimination of infected blood cells in vitro, immune reactivity and complications following HCMV infection

    Författare :Susanne Larsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human cytomegalovirus (HCMV) belongs to the herpes virus family and establishes life-long persistence in a latent state following a primary infection. HCMV disease causes high morbidity in immunosuppressed individuals, such as bone marrow and organ transplant patients. LÄS MER

  5. 9. Applications of nanospray desorption electrospray ionization mass spectrometry : In situ lipid and metabolite analysis from cells to tissue

    Författare :Hilde-Marléne Bergman; Ingela Lanekoff; Jonas Bergquist; Martina Marchetti-Deschmann; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mass spectrometry; mass spectrometry imaging MSI ; nanospray desorption electrospray ionization nano-DESI ; single-cell analysis; neurotransmitter imaging; diabetic nephropathy; pneumatic nebulization; lipidomics; metabolomics; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

    Sammanfattning : Ambient mass spectrometry (MS) has proved to be an important addition to the bioanalytical toolbox. These methods perform analyte sampling and ionization under atmospheric pressure, and require very little sample preparation other than the sampling process in front of the machine. LÄS MER

  7. 10. Formic acid adsorption and photodecomposition on rutile TiO2 (110) : An in situ infrared reflection absorption spectroscopy study

    Författare :Andreas Mattsson; Lars Österlund; Gunnar Niklasson; Claes-Göran Granqvist; Håkan Rensmo; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : TiO2 based photocatalysis is an emerging green nanotechnology that can be used forremoval of pollutants from water and air. It has had an increased research interest, bothfrom an application and fundamental point of view, during the last decades. LÄS MER