Sökning: "small intestine"
Visar resultat 11 - 15 av 204 avhandlingar innehållade orden small intestine.
11. Proteomic and Functional Analysis of In Vitro Systems for Studies of Drug Disposition in the Human Small Intestine and Liver
Sammanfattning : To reach the bloodstream, an orally administered drug must be absorbed through the small intestine and avoid extensive clearance in the liver. Estimating these parameters in vitro is therefore important in drug discovery and development. LÄS MER
12. Membrane transport and the human small intestine : Relation to mucosal protection, intestinal anaphylaxis and nitric oxide
Sammanfattning : The tightly adherent monolayer of epithelial cells that line the luminal side of the intestine provides a dynamic and highly regulated barrier to the passive and active transport of ions, water and macromolecules. Cathecol-O-methyl transferase inhibition prevents tissue degradation of catecholaminesincluding dopamine and intracellular carbonic anhydrase activity is an important regulator of ion and water transport in the small intestine. LÄS MER
13. Proteomics-informed analysis of drug disposition in the human liver and small intestine
Sammanfattning : Orally administered drugs are absorbed in the intestine and generally metabolized in the liver. Therefore, understanding factors determining drug distribution and elimination in these tissues is important. LÄS MER
14. Novel Circulating and Tissue Biomarkers for Small Intestine Neuroendocrine Tumors and Lung Carcinoids
Sammanfattning : Small intestine neuroendocrine tumors (SI-NETs) and lung carcinoids (LCs) are relatively indolent tumors, which originate from neuroendocrine (NE) cells of the diffuse NE system. Metastases can spread before diagnosis. Thus, potential cures become unavailable, which entitles new biomarker development. LÄS MER
15. Digestion and Absorption of Sphingomyelin from Milk
Sammanfattning : Sphingomyelin (SM) is a major component of mammalian cell membranes. Due to its widespread occurrence it is a dietary component, occurring mainly in milk, eggs, meat and fish. In the cell membrane SM was earlier considered to be only a structural element, which interacts with cholesterol and forms a system for bilayer stabilization. LÄS MER