Sökning: "small animal PET"

Visar resultat 1 - 5 av 17 avhandlingar innehållade orden small animal PET.

1. 1. Methodological developments in small animal PET neuroimaging

   Författare :Miklós Tóth; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Positron emission tomography (PET) is a nuclear imaging technique using a multidisciplinary approach to functionally visualize processes in the brain or other living tissue. It is capable to determine the pharmacokinetic and pharmacodynamic properties of a molecule in the CNS, with a low risk of side effects on the subject. LÄS MER

3. 2. Translational PET imaging of inflammation

   Författare :Emmi Puuvuori; Olof Eriksson; Tove Grönroos; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PET imaging; Nuclear Medicine; Inflammation; Translational Medicine;

   Sammanfattning : Inflammation is our body’s sophisticated defense mechanism against invading pathogens, traumas, and tumors. Repeatable and non-invasive monitoring of inflammation process would open opportunities to improve our knowledge of several diseases and enable assessment of personalized treatments. LÄS MER

4. 3. Development of Palladium-Promoted 11C/12C-Carbonylations and Radiosynthesis of Amyloid PET Ligands

   Författare :Patrik Nordeman; Gunnar Antoni; Mats Larhed; Luke R Odell; Antony D Gee; Uppsala universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Palladium; Carbonylation; Positron emission tomography; PET; Carbon-11; Fluor-18; Radiochemistry; Amyloidosis; Palladium; Karbonyleringar; Positronemissionstomografi; PET; Kol-11; Fluor-18; Radiokemi; Amyloidos; Pharmaceutical Science; Farmaceutisk vetenskap; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi; Medicinal Chemistry; Läkemedelskemi;

   Sammanfattning : In the first part of this thesis, palladium(0)-catalyzed and -mediated carbonylations are discussed. Paper I describes a new method for the safe, efficient use of a solid carbon monoxide source in the synthesis of primary and secondary benzamides. LÄS MER

5. 4. Software Solutions for Nuclear Imaging Systems in Cardiology, Small Animal Research and Education

   Författare :Iván Valastyán; Andras Kerek; Michael Ljungberg; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical technology; Medicinsk teknik;

   Sammanfattning : The sensitivity for observing physiological processes makes nuclear imaging an important tool in medical diagnostics. Different types of nuclear imaging modalities, with emphasis on the software components and image reconstructions, are presented in this thesis:  the Cardiotom for myocardial heart studies at the Karolinska University Hospital, the small animal Positron Emission Tomograph (PET) scanners for research and the SPECT, PET, spiral CT and Cardiotom demonstrators for the Royal Institute of Technology medical imaging laboratory. LÄS MER

7. 5. Targeting molecules for diagnostics of Head and Neck squamous cell carcinoma

   Författare :Anna-Karin Haylock; Marika Nestor; Göran Laurell; Matti Anniko; Katrine Riklund; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HNSCC; CD44v6; radio-immunodiagnosis; immuno-PET; tumor targeting; antibodies; antibody fragments; Oto-Rhino-Laryngology; Oto-rhino-laryngologi;

   Sammanfattning : To personalize treatment for cancer, correct staging of the primary tumor, nodal disease and metastatic disease is of essence. By targeting tumor specific receptors with radiolabeled antibodies, specificity and accuracy of imaging may be improved. LÄS MER