Sökning: "skinned muscle fiber"

Hittade 2 avhandlingar innehållade orden skinned muscle fiber.

  1. 1. Adaptability of skeletal muscle to hormone treatment in relation to gender and aging

    Författare :Fushun Yu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :skinned muscle fiber; gender; aging; steroid hormone; V0 electrophoresis; MyHC; MyLC; enzymehistochemistry; hyperthyroid rat; thyroid hormone receptor TR deficient TR[alpha]1 - -; TR[beta]- -; and TR[alpha]1- -[beta]- - mice;

    Sammanfattning : The aims of this study were to investigate the expression of myosin isoforms, muscle contractility at the cell level, and changes in these parameters in response to altered hormonal status in aging male and female rodents. In addition, by using mice lacking thyroid hormone receptors (TR[alpha]1 or TR[beta] or TR[alpha]1/[beta]) we tried to improve our understanding of the mechanisms by which thyroid hormone regulates the expression of specific MyHC isoforms via these different nuclear receptors. LÄS MER

  2. 2. Celluar and Molecular Mechanisms Underlying Regulation of Skeletal Muscle Contraction in Health and Disease

    Författare :Mingxin Li; Lars Larsson; Tomas Winkler; Alf Månsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Scaling; myosin heavy chain; in vitro motility assay; myopathy; Clinical neurophysiology; Klinisk neurofysiologi; Neuroscience; Neurovetenskap;

    Sammanfattning : Morphological changes, genetic modifications, and cell functional alterations are not always parallel. Therefore, assessment of skeletal muscle function is an integral part of the etiological approach. LÄS MER